Objectively Measured Physical Activity and Body Fatness: Associations with Total Body Fat, Visceral Fat, and Liver Fat.
Accelerometry
Adipose Tissue
/ anatomy & histology
Adiposity
Aged
Cross-Sectional Studies
Electric Impedance
Electrocardiography, Ambulatory
Exercise
Female
Humans
Intra-Abdominal Fat
/ anatomy & histology
Liver
/ anatomy & histology
Magnetic Resonance Imaging
Magnetic Resonance Spectroscopy
Male
Middle Aged
Triglycerides
/ metabolism
Journal
Medicine and science in sports and exercise
ISSN: 1530-0315
Titre abrégé: Med Sci Sports Exerc
Pays: United States
ID NLM: 8005433
Informations de publication
Date de publication:
01 11 2021
01 11 2021
Historique:
pubmed:
4
6
2021
medline:
23
11
2021
entrez:
3
6
2021
Statut:
ppublish
Résumé
It remains unclear to what extent habitual physical activity and sedentary time (ST) are associated with visceral fat and liver fat. We studied the substitution of ST with time spent physically active and total body fat (TBF), visceral adipose tissue (VAT), and hepatic triglyceride content (HTGC) in middle-age men and women. In this cross-sectional analysis of the Netherlands Epidemiology of Obesity study, physical activity was assessed in 228 participants using a combined accelerometer and heart rate monitor. TBF was assessed by the Tanita bioelectrical impedance, VAT by magnetic resonance imaging, and HTGC by proton-MR spectroscopy. Behavioral intensity distribution was categorized as ST, time spent in light physical activity (LPA), and moderate to vigorous physical activity (MVPA). To estimate the effect of replacing 30 min·d-1 of ST with 30 min·d-1 LPA or MVPA, we performed isotemporal substitution analyses, adjusted for sex, age, ethnicity, education, the Dutch Healthy Diet index, and smoking. Included participants (41% men) had a mean ± SD age of 56 ± 6 yr and spent 88 ± 56 min in MVPA and 9.0 ± 2.1 h of ST. Replacing 30 min·d-1 of ST with 30 min of MVPA was associated with 1.3% less TBF (95% confidence interval = -2.0 to -0.7), 7.8 cm2 less VAT (-11.6 to -4.0), and 0.89 times HTGC (0.82-0.97). Replacement with LPA was not associated with TBF (-0.03%; -0.5 to 0.4), VAT (-1.7 cm2; -4.4 to 0.9), or HTGC (0.98 times; 0.92-1.04). Reallocation of time spent sedentary with time spent in MVPA, but not LPA, was associated with less TBF, visceral fat, and liver fat. These findings contribute to the development of more specified guidelines on ST and physical activity.
Identifiants
pubmed: 34081059
doi: 10.1249/MSS.0000000000002712
pii: 00005768-202111000-00011
pmc: PMC7611840
mid: EMS134130
doi:
Substances chimiques
Triglycerides
0
Banques de données
ClinicalTrials.gov
['NCT03410316']
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
2309-2317Subventions
Organisme : Medical Research Council
ID : MC_UU_00006/4
Pays : United Kingdom
Organisme : Medical Research Council
ID : MC_UU_12015/3
Pays : United Kingdom
Informations de copyright
Copyright © 2021 by the American College of Sports Medicine.
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