Impact of COVID-19 pandemic on HIV viremia: a single-center cohort study in northern Italy.
Adherence
COVID-19
Follow-up
HIV continuum of care
HIV viremia
Public health
SARS-CoV-2
Journal
AIDS research and therapy
ISSN: 1742-6405
Titre abrégé: AIDS Res Ther
Pays: England
ID NLM: 101237921
Informations de publication
Date de publication:
04 06 2021
04 06 2021
Historique:
received:
06
02
2021
accepted:
27
05
2021
entrez:
5
6
2021
pubmed:
6
6
2021
medline:
22
6
2021
Statut:
epublish
Résumé
Brescia Province, northern Italy, was one of the worst epicenters of the COVID-19 pandemic. The division of infectious diseases of ASST (Azienda Socio Sanitaria Territoriale) Spedali Civili Hospital of Brescia had to face a great number of inpatients with severe COVID-19 infection and to ensure the continuum of care for almost 4000 outpatients with HIV infection actively followed by us. In a recent manuscript we described the impact of the pandemic on continuum of care in our HIV cohort expressed as number of missed visits, number of new HIV diagnosis, drop in ART (antiretroviral therapy) dispensation and number of hospitalized HIV patients due to SARS-CoV-2 infection. In this short communication, we completed the previous article with data of HIV plasmatic viremia of the same cohort before and during pandemic. We considered all HIV-patients in stable ART for at least 6 months and with at least 1 available HIV viremia in the time window March 01-November 30, 2019, and another group of HIV patients with the same two requisites but in different time windows of the COVID-19 period (March 01-May 31, 2020, and June 01-November 30, 2020). For patients with positive viremia (PV) during COVID-19 period, we reported also the values of viral load (VL) just before and after PV. the percentage of patients with PV during COVID-19 period was lower than the previous year (2.8% vs 7%). Only 1% of our outpatients surely suffered from pandemic in term of loss of previous viral suppression. Our efforts to limit the impact of pandemic on our HIV outpatients were effective to ensure HIV continuum of care.
Sections du résumé
BACKGROUND
Brescia Province, northern Italy, was one of the worst epicenters of the COVID-19 pandemic. The division of infectious diseases of ASST (Azienda Socio Sanitaria Territoriale) Spedali Civili Hospital of Brescia had to face a great number of inpatients with severe COVID-19 infection and to ensure the continuum of care for almost 4000 outpatients with HIV infection actively followed by us. In a recent manuscript we described the impact of the pandemic on continuum of care in our HIV cohort expressed as number of missed visits, number of new HIV diagnosis, drop in ART (antiretroviral therapy) dispensation and number of hospitalized HIV patients due to SARS-CoV-2 infection. In this short communication, we completed the previous article with data of HIV plasmatic viremia of the same cohort before and during pandemic.
METHODS
We considered all HIV-patients in stable ART for at least 6 months and with at least 1 available HIV viremia in the time window March 01-November 30, 2019, and another group of HIV patients with the same two requisites but in different time windows of the COVID-19 period (March 01-May 31, 2020, and June 01-November 30, 2020). For patients with positive viremia (PV) during COVID-19 period, we reported also the values of viral load (VL) just before and after PV.
RESULTS
the percentage of patients with PV during COVID-19 period was lower than the previous year (2.8% vs 7%). Only 1% of our outpatients surely suffered from pandemic in term of loss of previous viral suppression.
CONCLUSIONS
Our efforts to limit the impact of pandemic on our HIV outpatients were effective to ensure HIV continuum of care.
Identifiants
pubmed: 34088307
doi: 10.1186/s12981-021-00355-x
pii: 10.1186/s12981-021-00355-x
pmc: PMC8177258
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
31Références
Int J Environ Res Public Health. 2020 Jun 24;17(12):
pubmed: 32599783
Lancet HIV. 2020 May;7(5):e308-e309
pubmed: 32272084
AIDS Res Ther. 2020 Oct 4;17(1):59
pubmed: 33012282
AIDS. 2021 Mar 1;35(3):355-358
pubmed: 33252488
Lancet. 2020 Nov 28;396(10264):1703
pubmed: 33248482
AIDS Behav. 2020 Oct;24(10):2760-2763
pubmed: 32385679
Trop Med Health. 2020 May 13;48:32
pubmed: 32425653
AIDS Behav. 2020 Sep;24(9):2486-2489
pubmed: 32347403
J Int AIDS Soc. 2020 Oct;23(10):e25627
pubmed: 33047483
AIDS. 2020 Dec 1;34(15):2328-2331
pubmed: 32910069
AIDS Behav. 2020 Oct;24(10):2770-2772
pubmed: 32382823