Auricular and periauricular melanomas have similar clinicopathologic factors and survival rates.


Journal

Journal of cosmetic dermatology
ISSN: 1473-2165
Titre abrégé: J Cosmet Dermatol
Pays: England
ID NLM: 101130964

Informations de publication

Date de publication:
Apr 2022
Historique:
revised: 28 05 2021
received: 20 02 2021
accepted: 02 06 2021
pubmed: 6 6 2021
medline: 6 4 2022
entrez: 5 6 2021
Statut: ppublish

Résumé

Auricular melanomas are rare malignancies, and conflicting reports regarding their clinical behaviors have been published so far. In this study, we investigated the clinical features of the auricular melanomas and compared them with periauricular skin melanomas. Data of 53 primary melanomas arising in auricular (n = 25) and periauricular regions (n = 28) were analyzed retrospectively. Demographic, histopathological, and clinical characteristics were found similar between auricular and periauricular melanomas (p > 0.05). Likewise, the recurrence rates for both groups were found to be similar (30%) (p = 0.9). The 5-year relapse-free survival rate of all patients was 57.4%, and no statistical difference was observed between the two groups-63.9% for auricular melanomas and 51.7% for periauricular melanomas (p = 0.5). Moreover, the 5-year overall survival rate of all melanomas was 46.9%, and there was no statistical significance between the two groups-56.1% and 37.4% for auricular and periauricular melanomas, respectively (p = 0.4). Auricular and periauricular melanomas share similar clinicopathologic features and outcomes.

Sections du résumé

BACKGROUND BACKGROUND
Auricular melanomas are rare malignancies, and conflicting reports regarding their clinical behaviors have been published so far.
OBJECTIVE OBJECTIVE
In this study, we investigated the clinical features of the auricular melanomas and compared them with periauricular skin melanomas.
METHODS METHODS
Data of 53 primary melanomas arising in auricular (n = 25) and periauricular regions (n = 28) were analyzed retrospectively.
RESULTS RESULTS
Demographic, histopathological, and clinical characteristics were found similar between auricular and periauricular melanomas (p > 0.05). Likewise, the recurrence rates for both groups were found to be similar (30%) (p = 0.9). The 5-year relapse-free survival rate of all patients was 57.4%, and no statistical difference was observed between the two groups-63.9% for auricular melanomas and 51.7% for periauricular melanomas (p = 0.5). Moreover, the 5-year overall survival rate of all melanomas was 46.9%, and there was no statistical significance between the two groups-56.1% and 37.4% for auricular and periauricular melanomas, respectively (p = 0.4).
CONCLUSION CONCLUSIONS
Auricular and periauricular melanomas share similar clinicopathologic features and outcomes.

Identifiants

pubmed: 34089217
doi: 10.1111/jocd.14278
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1570-1573

Informations de copyright

© 2021 Wiley Periodicals LLC.

Références

Ravin AG, Pickett N, Johnson JL, Fisher SR, Levin LS, Seigler HF. Melanoma of the ear: treatment and survival probabilities based on 199 patients. Ann Plast Surg. 2006;57:70-76.
Toia F, Garbo G, Tripoli M, Rinaldi G, Moschella F, Cordova A. A systemic review on external ear melanoma. J Plast Reconstr Aesthet Surg. 2015;68:883-894.
Mondin V, Rinaldo A, Shaha AR, et al. Malignant melanoma of the auricle. Acta Oto-Laryngol. 2005;125:1140-1144.
Sawyer JD, Wilson ML, Neumeister MW. A systemic review of surgical management of melanoma of the external ear. Plast Reconstr Surg Glob Open. 2018;6:e1755.
Fiorio LM, Diniz LM, Spelta K, Badaro BA. Ear melanoma a four-case series. An Bras Dermatol. 2021;96:64-67.
Jahn V, Breuninger H, Garbe C, Moehrle M. Melanoma of the ear: prognostic factors and surgical strategies. Br J Dermatol. 2006;154:310-318.
Patel TD, Chin OY, Baredes S, Eloy JA, Ying YLM. A population based analysis of melanoma of the external ear. Otol Neurol. 2018;39:e137-e142.
Deep NL, Glasgow AE, Habermann EB, Kasperbauer JL, Carlson ML. Melanoma of the external ear: a population-based study. Am J Otolaryngol. 2017;38:309-315.

Auteurs

Faruk Tas (F)

Institute of Oncology, Istanbul University, Istanbul, Turkey.

Kayhan Erturk (K)

Department of Medical Oncology, Koc University, Istanbul, Turkey.

Ferhat Ferhatoglu (F)

Institute of Oncology, Istanbul University, Istanbul, Turkey.

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Classifications MeSH