Epidemiology and clinical characteristics of Klebsiella spp. meningitis in France.

France / epidemiology Humans Klebsiella Klebsiella Infections / complications Meningitis, Bacterial / complications Retrospective Studies
Klebsiella pneumoniae Meningitis Neurosurgery Nosocomial infection

Journal

Infectious diseases now
ISSN: 2666-9919
Titre abrégé: Infect Dis Now
Pays: France
ID NLM: 101775152

Informations de publication

Date de publication:
Mar 2022
Historique:
received: 02 03 2021
revised: 30 04 2021
accepted: 25 05 2021
pubmed: 7 6 2021
medline: 4 3 2022
entrez: 6 6 2021
Statut: ppublish

Résumé

To describe the epidemiology of Klebsiella spp. meningitis in France with respect to clinical and bacteriological data. We performed a four-year multicenter, retrospective, observational study. The primary objective was to provide a clinical description of patients with Klebsiella spp. meningitis. Secondary objectives were to compare community-acquired meningitis and healthcare-associated meningitis and to analyze factors associated with mortality. We enrolled 131 patients with Klebsiella spp. meningitis. Eighty-two (62.6%) infections were reported following neurosurgery. Twenty-eight strains (21.4%) were resistant to third-generation cephalosporins (3GC). The median [IQR] cellularity was 980/mm Purulent meningitis caused by Klebsiella spp. needs to be considered in patients with community-acquired meningitis and preexisting conditions, as well as in case of meningitis following neurosurgical procedures.

Identifiants

DOI: 10.1016/j.idnow.2021.05.006 PMID: 34091093
pubmed: 34091093
pii: S2666-9919(21)00115-9
doi: 10.1016/j.idnow.2021.05.006
pii:
doi:

Types de publication

Journal Article Multicenter Study Observational Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

82-86

Commentaires et corrections

Type : CommentIn

Informations de copyright

Copyright © 2021 Elsevier Masson SAS. All rights reserved.

Auteurs

B Pilmis (B)

Équipe mobile de microbiologie clinique, groupe hospitalier Paris Saint-Joseph, Paris, France; Institut Micalis UMR 1319, université Paris-Saclay, INRAe, AgroParisTech, Châtenay-Malabry, France; Service de microbiologie clinique, GH Paris Saint-Joseph, 75014 Paris, France; Service de maladies infectieuses et tropicales, hôpital Necker-Enfants-Malades, Paris, France. Electronic address: bpilmis@ghpsj.fr.

G Péan de Ponfilly (G)

Institut Micalis UMR 1319, université Paris-Saclay, INRAe, AgroParisTech, Châtenay-Malabry, France; Service de microbiologie clinique, GH Paris Saint-Joseph, 75014 Paris, France; Laboratoire de bactériologie, département des agents infectieux, CHU Saint-Louis-Lariboisière-Fernand-Widal, AP-HP, 75010 Paris, France.

E Farfour (E)

Service de biologie clinique, hôpital Foch, 92150 Suresnes, France.

A-G Ranc (AG)

Institut des agents infectieux (IAI), hospices civils de Lyon, Lyon, France.

V Fihman (V)

Unité de bactériologie, groupe hospitalier Henri-Mondor, 94010 Créteil, France.

E Bille (E)

Laboratoire de microbiologie, hôpital Necker-Enfants-Malades, 75015 Paris, France.

L Dortet (L)

Service de bactériologie-hygiène, CHU de Bicêtre, 94270 Le Kremlin-Bicêtre, France.

N Degand (N)

Laboratoire de bactériologie, hôpital Larchet, CHU Nice, 06202 Nice, France.

P Morand (P)

Université de Paris, faculté de médecine Paris Centre, groupe hospitalier AP-HP-CUP, service de bactériologie, 75014 Paris, France.

A Potron (A)

Centre national de référence de la résistance aux antibiotiques, centre hospitalier universitaire de Besançon, UMR6249 CNRS chrono-environnement, université de Franche-Comté, Besançon, France.

A Mizrahi (A)

Institut Micalis UMR 1319, université Paris-Saclay, INRAe, AgroParisTech, Châtenay-Malabry, France; Service de microbiologie clinique, GH Paris Saint-Joseph, 75014 Paris, France; Laboratoire de microbiologie et plateforme de dosage des anti-infectieux, groupe hospitalier Paris Saint-Joseph, Paris, France.

F Laurent (F)

Service de biologie clinique, hôpital Foch, 92150 Suresnes, France.

C Le Brun (C)

Service de bactériologie-virologie-hygiène, hôpital Bretonneau, CHRU de Tours, 37000 Tours, France.

T Guillard (T)

Université de Reims-Champagne-Ardenne, Inserm UMR-S 1250 P3Cell, SFR CAP-santé, laboratoire de bactériologie-virologie-hygiène hospitalière-parasitologie-mycologie, hôpital Robert-Debré, CHU Reims, 51000 Reims, France.

G Héry-Arnaud (G)

Université de Brest, Inserm, UMR 1078, unité de bactériologie, CHRU de Brest, 29200 Brest, France.

C Piau (C)

Service de bactériologie-hygiène hospitalière, CHU de Rennes, 35033 Rennes, France.

O Barraud (O)

Service de bactériologie, virologie, hygiène, CHU Dupuytren, 2, avenue Martin-Luther-King, 87042 Limoges, France.

L Ruffier d'Epenoux (L)

Service de bactériologie-hygiène hospitalière, CHU de Nantes, institut de biologie, 9, quai Moncousu, 44093 Nantes cedex 1, France.

J-R Zahar (JR)

Hygiène hospitalière et prévention du risque infectieux, CHU Avicenne, AP-HP, 125, rue de Stalingrad, 93000 Bobigny, France.

A Le Monnier (A)

Institut Micalis UMR 1319, université Paris-Saclay, INRAe, AgroParisTech, Châtenay-Malabry, France; Service de microbiologie clinique, GH Paris Saint-Joseph, 75014 Paris, France; Laboratoire de bactériologie, département des agents infectieux, CHU Saint-Louis-Lariboisière-Fernand-Widal, AP-HP, 75010 Paris, France.

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Classifications MeSH

questionsmedicales.fr › Régions géographiques › Europe › France › Epidemiology and clinical characteristics of...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Epidemiology and clinical characteristics of...
questionsmedicales.fr › Bactéries › Proteobacteria › Gammaproteobacteria › Enterobacteriaceae › Klebsiella › Epidemiology and clinical characteristics of...
questionsmedicales.fr › Infection › Infections bactériennes et mycoses › Infections bactériennes › Infections bactériennes à Gram négatif › Infections à Enterobacteriaceae › Infections à Klebsiella › Epidemiology and clinical characteristics of...
questionsmedicales.fr › Maladies du système nerveux › Méningite › Méningite bactérienne › Epidemiology and clinical characteristics of...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Études rétrospectives › Epidemiology and clinical characteristics of...