Volumetry and Surgical Grading Systems for Vestibular Schwannoma Size Assessment and their Relationship to Postoperative Facial Nerve Function.


Journal

Journal of neurological surgery. Part A, Central European neurosurgery
ISSN: 2193-6323
Titre abrégé: J Neurol Surg A Cent Eur Neurosurg
Pays: Germany
ID NLM: 101580767

Informations de publication

Date de publication:
Jan 2022
Historique:
pubmed: 9 6 2021
medline: 4 2 2022
entrez: 8 6 2021
Statut: ppublish

Résumé

 Treatment modalities in vestibular schwannoma (VS) are difficult to compare since different techniques for size measurements are used. The purpose of this study was to evaluate the relation between different tumor size grading systems regarding their compatibility as well as the relationship to facial nerve outcome facilitating comparisons of different studies.  In this retrospective study, preoperative magnetic resonance imaging of 100 patients with surgically treated VS was evaluated regarding total tumor volume and anatomical extension based on the Koos and Samii classification, as well as volumetric and maximal diameter measures. Three-dimensional constructive interference in steady state (3D-CISS) and T1 postcontrast volumetric interpolated breath-hold examination (VIBE) sequences were used. Facial nerve function was evaluated according to the House-Brackmann (HB) scale 6 months following complete tumor removal via the retrosigmoid approach.  Tumor size showed a moderate influence on postsurgical facial nerve function with correlations not exceeding 0.4. Severe palsy was observed mainly in patients with large tumors with Koos grade 4, Samii grade 4b, respectively a volume of at least 6 cm  The results of our study allow direct comparison of studies on surgery versus radiotherapy of VS. The data allow for translation of tumor sizes based on different grading systems. Comparison of microsurgical, radiotherapeutic and radiosurgical approaches should concentrate on patients with large tumors. Whereas smaller tumors were rarely associated with severe facial palsy, large tumors did not exclude the possibility of weak or no palsy 6 months after surgery.

Sections du résumé

BACKGROUND AND STUDY AIMS OBJECTIVE
 Treatment modalities in vestibular schwannoma (VS) are difficult to compare since different techniques for size measurements are used. The purpose of this study was to evaluate the relation between different tumor size grading systems regarding their compatibility as well as the relationship to facial nerve outcome facilitating comparisons of different studies.
MATERIAL AND METHODS METHODS
 In this retrospective study, preoperative magnetic resonance imaging of 100 patients with surgically treated VS was evaluated regarding total tumor volume and anatomical extension based on the Koos and Samii classification, as well as volumetric and maximal diameter measures. Three-dimensional constructive interference in steady state (3D-CISS) and T1 postcontrast volumetric interpolated breath-hold examination (VIBE) sequences were used. Facial nerve function was evaluated according to the House-Brackmann (HB) scale 6 months following complete tumor removal via the retrosigmoid approach.
RESULTS RESULTS
 Tumor size showed a moderate influence on postsurgical facial nerve function with correlations not exceeding 0.4. Severe palsy was observed mainly in patients with large tumors with Koos grade 4, Samii grade 4b, respectively a volume of at least 6 cm
CONCLUSIONS CONCLUSIONS
 The results of our study allow direct comparison of studies on surgery versus radiotherapy of VS. The data allow for translation of tumor sizes based on different grading systems. Comparison of microsurgical, radiotherapeutic and radiosurgical approaches should concentrate on patients with large tumors. Whereas smaller tumors were rarely associated with severe facial palsy, large tumors did not exclude the possibility of weak or no palsy 6 months after surgery.

Identifiants

pubmed: 34100269
doi: 10.1055/s-0041-1725951
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

39-45

Informations de copyright

Thieme. All rights reserved.

Déclaration de conflit d'intérêts

None declared

Auteurs

Catharina Strauss (C)

Department of Neuroradiology, University Hospital Erlangen, Erlangen, Germany.

Stefan Rampp (S)

Department of Neurosurgery, University Hospital Halle (Saale), Halle (Saale), Germany.

Christian Scheller (C)

Department of Neurosurgery, University of Halle-Wittenberg, Halle, Germany.

Julian Prell (J)

Department of Neurosurgery, University Hospital Halle (Saale), Halle (Saale), Germany.

Christian Strauss (C)

Department of Neurosurgery, University Hospital Halle (Saale), Halle (Saale), Germany.

Arnd Doerfler (A)

Department of Neuroradiology, University Hospital Erlangen, Erlangen, Germany.

Tobias Engelhorn (T)

Department of Neuroradiology, University Hospital Erlangen, Erlangen, Germany.

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