Long-term follow-up of children treated with the Repiphysis expandable prosthesis for lower extremity bone sarcoma.


Journal

Journal of pediatric orthopedics. Part B
ISSN: 1473-5865
Titre abrégé: J Pediatr Orthop B
Pays: United States
ID NLM: 9300904

Informations de publication

Date de publication:
01 Mar 2022
Historique:
pubmed: 9 6 2021
medline: 3 2 2022
entrez: 8 6 2021
Statut: ppublish

Résumé

Expandable endoprostheses provide a limb salvage option for skeletally immature patients with bone sarcoma of the lower extremities. Initial reports of the Repiphysis prosthesis were encouraging; however, medium-term follow-up revealed high complication rates. We report on the long-term follow-up of a cohort of patients treated with the Repiphysis prosthesis. Eleven patients were included in the study. Data collected included sex, age at surgery, duration of follow-up, site of disease, histologic diagnosis, number of lengthening sessions, amount lengthened, postoperative complications, endoprosthetic failure, mode of endoprosthetic failure, duration from index surgery to failure and to revision, type of revision surgery and final limb-length discrepancy. The average duration of follow-up from the time of surgery was 180 months (range, 144-215 months). Fifteen Repiphysis implants were used in 11 patients. All implants failed with an average time from surgery to failure of 36 months (range, 3-72 months). Twenty-four complications were observed: one wound dehiscence, two deep infections, 18 mechanical failures, implant collapse with destruction of proximal tibia epiphysis in two and one periprosthetic proximal femur fracture with dislodgement of the stem. Despite being an option for limb salvage, the Repiphysis prosthesis has a high rate of mechanical failure and need for revision, similar to other expandable implants. The authors, therefore, recommend full disclosure of the potential short- and long-term complications and need for revision, as well as alternative treatment options if their use is considered. Level of evidence: IV (Therapeutic).

Identifiants

pubmed: 34101677
doi: 10.1097/BPB.0000000000000891
pii: 01202412-202203000-00038
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

e258-e263

Informations de copyright

Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.

Références

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Auteurs

Karim Masrouha (K)

Divisions of Pediatric Orthopedic Surgery and Orthopedic Oncology, Department of Orthopedic Surgery, NYU Langone Health, New York, New York, USA.

Miguel Abboud (M)

Department of Pediatrics and Adolescent Medicine, American University of Beirut Medical Center, Children's Cancer Institute.

Raya Saab (R)

Department of Pediatrics and Adolescent Medicine, American University of Beirut Medical Center, Children's Cancer Institute.

Samar A Muwakkit (SA)

Department of Pediatrics and Adolescent Medicine, American University of Beirut Medical Center, Children's Cancer Institute.

Nabil Khoury (N)

Department of Diagnostic Radiology.

Rachid Haidar (R)

Division of Orthopedic surgery, Department of Surgery, American University of Beirut Medical Center, Beirut, Lebanon.

Said Saghieh (S)

Division of Orthopedic surgery, Department of Surgery, American University of Beirut Medical Center, Beirut, Lebanon.

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