Significant increases of the amygdala between immediate and late postpartum: Pronounced effects within the superficial subregion.
MRI
amygdala
anxiety
gray matter
postpartum
pregnancy
Journal
Journal of neuroscience research
ISSN: 1097-4547
Titre abrégé: J Neurosci Res
Pays: United States
ID NLM: 7600111
Informations de publication
Date de publication:
09 2021
09 2021
Historique:
revised:
08
04
2021
received:
22
01
2021
accepted:
02
05
2021
pubmed:
9
6
2021
medline:
11
2
2022
entrez:
8
6
2021
Statut:
ppublish
Résumé
Research exploring the underlying neuroanatomical correlates of early motherhood seems to suggest that the period after giving birth is marked by tissue increases in the mother's brain. While some studies point to the amygdala as one of the areas undergoing postpartum changes, existing analyses did not discriminate between the different subregions of this functionally heterogeneous structure. Thus, to further extend this understudied field of research and to better understand the potential role of the amygdala when transitioning to motherhood, we applied an advanced region-of-interest technique that enabled us to analyze the amygdala as a whole as well as its different subareas, specifically the left and right centromedian (CM), laterobasal (LB), and superficial (SF) regions. Comparing the brains of 14 healthy women between immediate postpartum (within 1-2 days of childbirth) and late postpartum (at 4-6 weeks after childbirth), we revealed increases of the amygdala. However, effects manifested differentially across subareas, with particularly strong effects for the SF region, moderate effects for the CM region, and no effects for the LB region. These findings might reflect region-specific adaptations of the mother's brain tuning into the distinct and ever-changing needs of a newborn, either as a cause for it or as a consequence thereof.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2261-2270Informations de copyright
© 2021 Wiley Periodicals LLC.
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