POSTOPERATIVE POSTERIOR SEGMENT COMPLICATIONS AFTER BOSTON TYPE 1 KERATOPROSTHESIS: Incidence, Risk Factors, and Intermediate-Term Outcomes.
Aged
Aged, 80 and over
Artificial Organs
Cornea
Female
Follow-Up Studies
Humans
Incidence
Male
Middle Aged
Posterior Eye Segment
/ pathology
Postoperative Complications
Prostheses and Implants
/ adverse effects
Prosthesis Implantation
Retinal Diseases
/ epidemiology
Retrospective Studies
Risk Factors
Treatment Outcome
Visual Acuity
/ physiology
Journal
Retina (Philadelphia, Pa.)
ISSN: 1539-2864
Titre abrégé: Retina
Pays: United States
ID NLM: 8309919
Informations de publication
Date de publication:
01 Dec 2021
01 Dec 2021
Historique:
pubmed:
11
6
2021
medline:
15
1
2022
entrez:
10
6
2021
Statut:
ppublish
Résumé
To identify the incidence of, risk factors for, and outcomes of posterior segment complications (PSC) after Boston Type 1 keratoprosthesis (KPro) implantation. Retrospective, consecutive case series of KPro procedures at the Stein Eye Institute. Data regarding ocular history, intraoperative details, postoperative management, and outcomes were collected. Eyes with at least one PSC (PSC group) were compared with eyes without PSC (No PSC group), and risk factors for PSC were determined. Ninety-five PSC occurred in 69/169 eyes (40.8%), at a mean of 20.1 months after KPro implantation (0.01 complications/eye month). The median follow-up after KPro implantation was 44.0 months (range 3.0-174.4). The most common PSC were epiretinal membrane (16.6%), cystoid macular edema (12.4%), vitritis (11.2%), and retinal detachment (9.5%). Previous retinal detachment repair, concomitant intraocular lens removal, postoperative aphakia, and vitritis were risk factors for retinal detachment. Postoperative infectious keratitis was a risk factor for epiretinal membrane, cystoid macular edema, and vitritis. The posterior segment complication group had a significantly higher rate of eyes failing to maintain visual acuity ≥20/200 (HR = 2.28; 95% CI = 1.35-3.85) and KPro retention failure rate (HR = 1.66; 95% CI = 0.95-2.91). Posterior segment complications occur in approximately 40% of eyes after KPro implantation, resulting in reduced visual outcomes and KPro retention.
Identifiants
pubmed: 34111883
doi: 10.1097/IAE.0000000000003233
pii: 00006982-202112000-00011
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2499-2509Références
Szigiato AA, Bostan C, Nayman T, Harissi-Dagher M. Long-term visual outcomes of the Boston type I keratoprosthesis in Canada. Br J Ophthalmol 2020;104:1601–1607.
Aravena C, Yu F, Aldave AJ. Long-term visual outcomes, complications, and retention of the Boston type I keratoprosthesis. Cornea 2018;37:3–10.
Ahmad S, Akpek EK, Gehlbach PL, et al. Predictors of visual outcomes following Boston type 1 keratoprosthesis implantation. Am J Ophthalmol 2015;159:739–747.
Ghaffari R, Bonnet C, Yung M, et al. Infectious keratitis after Boston type 1 keratoprosthesis implantation. Cornea 2020; In press.
Kim MJ, Yu F, Aldave AJ. Microbial keratitis after Boston type I keratoprosthesis implantation: incidence, organisms, risk factors, and outcomes. Ophthalmology 2013;120:2209–2216.
Lenis TL, Chiu SY, Law SK, et al. Safety of concurrent Boston type I keratoprosthesis and glaucoma drainage device implantation. Ophthalmology 2017;124:12–19.
Behlau I, Martin KV, Martin JN, et al. Infectious endophthalmitis in Boston keratoprosthesis: incidence and prevention. Acta ophthalmologica 2014;92:e546–555.
Goldman DR, Hubschman JP, Aldave AJ, et al. Postoperative posterior segment complications in eyes treated with the Boston type I keratoprosthesis. Retina 2013;33:532–541.
Klufas MA, Yannuzzi NA, D'Amico DJ, Kiss S. Vitreoretinal aspects of permanent keratoprosthesis. Surv Ophthalmol 2015;60:216–228.
Moshiri A, Safi M, Morse LS, et al. Posterior segment complications and impact on long-term visual outcomes in eyes with a type 1 Boston keratoprosthesis. Cornea 2019;38:1111–1116.
Lim JI, Machen L, Arteaga A, et al. Comparison of visual and anatomical outcomes of eyes undergoing type 1 boston keratoprosthesis with combination pars plana vitrectomy with eyes without combination vitrectomy. Retina 2018;38:S125–S133.
Johnson D, Robert MC, Bouhout S, Harissi-Dagher M. Vitritis after Boston keratoprosthesis type 1 implantation. Ophthalmol Retina 2018;2:1050–1055.
Iyer G, Srinivasan B, Agarwal S, et al. Keratoprostheses in silicone oil-filled eyes: long-term outcomes. Br J Ophthalmol 2019;103:781–788.
Aldave AJ, Kamal KM, Vo RC, Yu F. The Boston type I keratoprosthesis: improving outcomes and expanding indications. Ophthalmology 2009;116:640–651.
Nouri M, Durand ML, Dohlman CH. Sudden reversible vitritis after keratoprosthesis: an immune phenomenon?. Cornea 2005;24:915–919.
Bonnet C, Chehaibou I, Ghaffari R, et al. Idiopathic vitritis after Boston type 1 keratoprosthesis implantation: incidence, risk factors and outcomes in a multicentric cohort. Ocul Immunol Inflamm 2020; Epub ahead of print.
Greiner MA, Li JY, Mannis MJ. Longer-term vision outcomes and complications with the Boston type 1 keratoprosthesis at the University of California, Davis. Ophthalmology 2011;118:1543–1550.
Kiang L, Sippel KC, Starr CE, et al. Vitreoretinal surgery in the setting of permanent keratoprosthesis. Arch Ophthalmol 2012;130:487–492.
Perez VL, Leung EH, Berrocal AM, et al. Impact of total pars plana vitrectomy on postoperative complications in aphakic, snap-on, type 1 Boston keratoprosthesis. Ophthalmology 2017;124:1504–1509.
Park Y, Kim MH, Won JY, et al. Vitreoretinal complications after penetrating keratoplasty. Retina 2016;36:2110–2115.
Petousis V, Sallam AA, Haynes RJ, et al. Risk factors for retinal detachment following cataract surgery: the impact of posterior capsular rupture. Br J Ophthalmol 2016;100:1461–1465.
Ramos M, Kruger EF, Lashkari K. Biostatistical analysis of pseudophakic and aphakic retinal detachments. Semin Ophthalmol 2002;17:206–213.
Irvine AR. The pathogenesis of aphakic retinal detachment. Ophthalmic Surg 1985;16:101–107.
Jardeleza MS, Rheaume MA, Chodosh J, et al. Retinal detachments after Boston Keratoprosthesis: incidence, predisposing factors, and visual outcomes. Digital J Ophthalmol 2015;21:1–15.
Yaghouti F, Nouri M, Abad JC, et al. Keratoprosthesis: preoperative prognostic categories. Cornea 2001;20:19–23.
Bradley JC, Hernandez EG, Schwab IR, Mannis MJ. Boston type 1 keratoprosthesis: the university of California davis experience. Cornea 2009;28:321–327.
Kunavisarut P, Srisomboon T, Patikulsila D, et al. Risk factors for development of rhegmatogenous retinal detachment in patients with uveitis. Ocul Immunol Inflamm 2019;27:681–685.
Chan CC, LoVerde L, Qiang J, et al. Incidence, risk factors, and surgical management of Boston type 1 keratoprothesis corneal melts, leaks, and extrusions. Cornea 2016;35:1049–1056.
Bouhout S, Robert MC, Deli S, Harissi-Dagher M. Corneal melt after Boston keratoprosthesis: clinical presentation, management, outcomes and risk factor analysis. Ocul Immunol Inflamm 2018;26:693–699.