Dietary phytochemical index associated with cardiovascular risk factor in patients with type 1 diabetes mellitus.
Adolescent
Adult
Biomarkers
/ blood
Blood Glucose
/ metabolism
Cardiovascular Diseases
/ blood
Cholesterol, HDL
/ blood
Cholesterol, LDL
/ blood
Cross-Sectional Studies
Diabetes Mellitus, Type 1
/ blood
Diet
/ adverse effects
Female
Health Status
Heart Disease Risk Factors
Humans
Iran
/ epidemiology
Male
Nutritive Value
Phytochemicals
/ administration & dosage
Risk Assessment
Young Adult
Diabetes mellitus
adult
cardiovascular diseases
hyperglycemia
phytochemicals
Journal
BMC cardiovascular disorders
ISSN: 1471-2261
Titre abrégé: BMC Cardiovasc Disord
Pays: England
ID NLM: 100968539
Informations de publication
Date de publication:
12 06 2021
12 06 2021
Historique:
received:
13
02
2021
accepted:
08
06
2021
entrez:
13
6
2021
pubmed:
14
6
2021
medline:
12
10
2021
Statut:
epublish
Résumé
Dietary phytochemical index (DPI) is useful and inexpensive method to identify the role of phytochemicals on cardiovascular disease (CVD) risk factors. This study aimed to assess the relationship between DPI and CVD risk factors in patients with type1 diabetes mellitus. A total of 261 participants aged 18-35 years with T1DM were enrolled in this cross-sectional study to assess the relationship between DPI and CVD risk factors. Anthropometric measurements, blood lipids, glucose, and antioxidant level were measured. Food intakes were determined using a food frequency questionnaire to calculate DPI. Logistic regression was used. The mean age of participants was 25 years. After adjustment for potential confounders, participants in the highest tertile of DPI had 88 % lower chance of hyperglycemia (P for trend = 0.020), 81 % lower chance of low high-density lipoprotein cholesterol (HDL-C) (P for trend = 0.030) and 98 % lower chance of high low-density lipoprotein cholesterol to HDL-C ratio (P for tend = 0.040). There were no relationships between DPI and other CVD risk factors. Although higher intake of phytochemical-rich foods had a beneficial effect on some risk factors of CVD, more studies more studies are warranted to corroborate the present findings.
Sections du résumé
BACKGROUND
Dietary phytochemical index (DPI) is useful and inexpensive method to identify the role of phytochemicals on cardiovascular disease (CVD) risk factors. This study aimed to assess the relationship between DPI and CVD risk factors in patients with type1 diabetes mellitus.
METHODS
A total of 261 participants aged 18-35 years with T1DM were enrolled in this cross-sectional study to assess the relationship between DPI and CVD risk factors. Anthropometric measurements, blood lipids, glucose, and antioxidant level were measured. Food intakes were determined using a food frequency questionnaire to calculate DPI. Logistic regression was used.
RESULTS
The mean age of participants was 25 years. After adjustment for potential confounders, participants in the highest tertile of DPI had 88 % lower chance of hyperglycemia (P for trend = 0.020), 81 % lower chance of low high-density lipoprotein cholesterol (HDL-C) (P for trend = 0.030) and 98 % lower chance of high low-density lipoprotein cholesterol to HDL-C ratio (P for tend = 0.040). There were no relationships between DPI and other CVD risk factors.
CONCLUSIONS
Although higher intake of phytochemical-rich foods had a beneficial effect on some risk factors of CVD, more studies more studies are warranted to corroborate the present findings.
Identifiants
pubmed: 34118879
doi: 10.1186/s12872-021-02106-2
pii: 10.1186/s12872-021-02106-2
pmc: PMC8199677
doi:
Substances chimiques
Biomarkers
0
Blood Glucose
0
Cholesterol, HDL
0
Cholesterol, LDL
0
Phytochemicals
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
293Références
ARYA Atheroscler. 2014 Jul;10(4):203-10
pubmed: 25258636
Med Hypotheses. 2004;63(5):813-7
pubmed: 15488652
Diabetes Metab Res Rev. 2001 May-Jun;17(3):189-212
pubmed: 11424232
J Epidemiol. 2010;20(2):150-8
pubmed: 20154450
Avicenna J Phytomed. 2016 Sep-Oct;6(5):567-577
pubmed: 27761427
Int J Mol Sci. 2010 Mar 31;11(4):1365-402
pubmed: 20480025
J Diabetes Complications. 2003 Jan-Feb;17(1):7-10
pubmed: 12505749
J Hum Hypertens. 2016 Oct;30(10):573-80
pubmed: 27306085
J Am Diet Assoc. 2004 Nov;104(11):1725-7
pubmed: 15499362
Am J Clin Nutr. 2011 Feb;93(2):338-47
pubmed: 21106916
Diabetes Metab. 2009 Nov;35(5):353-60
pubmed: 19733492
Nutr Res. 2012 Jun;32(6):408-12
pubmed: 22749176
Int J Prev Med. 2018 Jul 30;9:64
pubmed: 30147853
J Am Coll Cardiol. 2014 Jul 1;63(25 Pt B):2889-934
pubmed: 24239923
Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2002 Dec;146(2):11-4
pubmed: 12572888
Diabetes Nutr Metab. 1999 Aug;12(4):256-63
pubmed: 10782751
Diabet Med. 2006 May;23(5):469-80
pubmed: 16681555
J Diabetes Metab Disord. 2013 Aug 13;12(1):43
pubmed: 23938049
Atherosclerosis. 2001 Jan;154(1):221-7
pubmed: 11137103
Plant Foods Hum Nutr. 2010 Mar;65(1):50-6
pubmed: 20094802
J Hum Nutr Diet. 2013 Jul;26 Suppl 1:145-53
pubmed: 23581519
Clin Nutr. 2013 Apr;32(2):200-6
pubmed: 22999066
Eur J Clin Nutr. 2016 Jan;70(1):10-6
pubmed: 26059745
Vasc Health Risk Manag. 2009;5:757-65
pubmed: 19774217
Eur J Nutr. 2017 Mar;56(2):663-670
pubmed: 26658900
Int J Food Sci Nutr. 2013 Feb;64(1):21-7
pubmed: 22816679
J Nutr. 2001 Aug;131(8):2184-91
pubmed: 11481415
Int J Food Sci Nutr. 2015;66(8):950-5
pubmed: 26600067
J Clin Lipidol. 2011 May-Jun;5(3):188-196
pubmed: 21600524
EXCLI J. 2014 May 06;13:451-3
pubmed: 26417272
Am J Hypertens. 2014 Jan;27(1):56-64
pubmed: 24014659
Nutrients. 2018 Dec 30;11(1):
pubmed: 30598006
J Hum Nutr Diet. 2010 Feb;23(1):20-9
pubmed: 19735350
Sci Rep. 2016 Mar 23;6:23625
pubmed: 27006201
Br J Nutr. 2010 Mar;103(6):842-50
pubmed: 19825207
Biol Res. 2015 Sep 04;48:49
pubmed: 26337448
Phytomedicine. 2016 Oct 15;23(11):1134-44
pubmed: 26778479