Noncollapsibility, confounding, and sparse-data bias. Part 2: What should researchers make of persistent controversies about the odds ratio?


Journal

Journal of clinical epidemiology
ISSN: 1878-5921
Titre abrégé: J Clin Epidemiol
Pays: United States
ID NLM: 8801383

Informations de publication

Date de publication:
11 2021
Historique:
received: 14 03 2021
revised: 04 06 2021
accepted: 04 06 2021
pubmed: 14 6 2021
medline: 21 12 2021
entrez: 13 6 2021
Statut: ppublish

Résumé

A previous note illustrated how the odds of an outcome have an undesirable property for risk summarization and communication: Noncollapsibility, defined as a failure of a group measure to represent a simple average of the measure over individuals or subgroups. The present sequel discusses how odds ratios amplify odds noncollapsibility and provides a basic numeric illustration of how noncollapsibility differs from confounding of effects (with which it is often confused). It also draws a connection of noncollapsibility to sparse-data bias in logistic, log-linear, and proportional-hazards regression.

Identifiants

pubmed: 34119647
pii: S0895-4356(21)00182-7
doi: 10.1016/j.jclinepi.2021.06.004
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

264-268

Informations de copyright

Copyright © 2021 Elsevier Inc. All rights reserved.

Auteurs

Sander Greenland (S)

Department of Epidemiology and Department of Statistics, University of California, CA, Los Angeles. Electronic address: lesdomes@ucla.edu.

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