Diffusion tensor imaging of renal cortex in lupus nephritis.


Journal

Japanese journal of radiology
ISSN: 1867-108X
Titre abrégé: Jpn J Radiol
Pays: Japan
ID NLM: 101490689

Informations de publication

Date de publication:
Nov 2021
Historique:
received: 20 04 2021
accepted: 08 06 2021
pubmed: 15 6 2021
medline: 26 11 2021
entrez: 14 6 2021
Statut: ppublish

Résumé

To evaluate the diagnostic value of diffusion tensor imaging (DTI) of renal cortex in assessment of lupus nephritis (LN) and prediction of its pathological subtypes. Prospective study was performed upon 39 female patients with pathologically proven LN and 16 sex- and age-matched healthy controls. Patients and controls underwent DTI of kidney. Mean diffusivity (MD) and fractional anisotropy (FA) of renal cortex were calculated by two radiologists. LN patients were pathologically classified into either non-proliferative (n = 15) or proliferative (n = 24). Mean MD of renal cortex in LN was significantly lower (p = 0.001) than that of controls with cut-off (2.16 and 2.2 X10 MD and FA of renal cortex may help to assess renal affection in LN patients and predict its pathological subtypes.

Identifiants

pubmed: 34125367
doi: 10.1007/s11604-021-01154-0
pii: 10.1007/s11604-021-01154-0
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1069-1076

Informations de copyright

© 2021. Japan Radiological Society.

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Auteurs

Ahmed Abdel Khalek Abdel Razek (AAKA)

Department of Diagnostic Radiology, Mansoura Faculty of Medicine, Mansoura, 13551, Egypt. arazek@mans.edu.eg.

Ahmed Mohamed Abdel Khalek (AMA)

Department of Diagnostic Radiology, Mansoura Faculty of Medicine, Mansoura, 13551, Egypt.

Samar Tharwat (S)

Rheumatology and Immunology Unit, Internal Medicine Department, Mansoura Faculty of Medicine, Mansoura, Egypt.

Mohammed Kamal Nassar (MK)

Mansoura Nephrology and Dialysis Unit, Internal Medicine Department, Mansoura Faculty of Medicine, Mansoura, Egypt.

Nihal Tharwat (N)

Department of Diagnostic Radiology, Mansoura Faculty of Medicine, Mansoura, 13551, Egypt.

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