Pharmacogenomics education, research and clinical implementation in the state of Minnesota.
Minnesota
implementation
pharmacogenomics
Journal
Pharmacogenomics
ISSN: 1744-8042
Titre abrégé: Pharmacogenomics
Pays: England
ID NLM: 100897350
Informations de publication
Date de publication:
07 2021
07 2021
Historique:
pubmed:
18
6
2021
medline:
11
2
2022
entrez:
17
6
2021
Statut:
ppublish
Résumé
Several healthcare organizations across Minnesota have developed formal pharmacogenomic (PGx) clinical programs to increase drug safety and effectiveness. Healthcare professional and student education is strong and there are multiple opportunities in the state for learners to gain workforce skills and develop advanced competency in PGx. Implementation planning is occurring at several organizations and others have incorporated structured utilization of PGx into routine workflows. Laboratory-based and translational PGx research in Minnesota has driven important discoveries in several therapeutic areas. This article reviews the state of PGx activities in Minnesota including educational programs, research, national consortia involvement, technology, clinical implementation and utilization and reimbursement, and outlines the challenges and opportunities in equitable implementation of these advances.
Identifiants
pubmed: 34137665
doi: 10.2217/pgs-2021-0058
pmc: PMC8265281
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
681-691Subventions
Organisme : AHRQ HHS
ID : K12 HS026379
Pays : United States
Organisme : NCATS NIH HHS
ID : KL2 TR002492
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR002494
Pays : United States
Références
Genet Med. 2019 Oct;21(10):2255-2263
pubmed: 30894703
Clin Cancer Res. 2002 Mar;8(3):768-74
pubmed: 11895907
Clin Pharmacol Ther. 1989 Aug;46(2):149-54
pubmed: 2758725
Clin Pharmacol Ther. 2016 Aug;100(2):160-9
pubmed: 26857349
Pharmacogenomics J. 2017 Jan;17(1):61-68
pubmed: 26667830
Cardiovasc Drugs Ther. 2021 Jun;35(3):549-559
pubmed: 32623598
Clin Pharmacol Ther. 2008 Jan;83(1):160-6
pubmed: 17882159
Pharmacogenomics. 2019 Aug;20(12):903-913
pubmed: 31453774
Anal Biochem. 2000 Feb 15;278(2):175-84
pubmed: 10660460
Pharmacogenomics J. 2019 Aug;19(4):375-389
pubmed: 30442921
Genome Res. 2017 Oct;27(10):1743-1751
pubmed: 28847918
JAMA. 2009 Oct 7;302(13):1429-36
pubmed: 19809024
Hum Immunol. 2020 Aug;81(8):423-429
pubmed: 32546429
Pharmacogenomics J. 2018 May 22;18(3):501-505
pubmed: 29160300
Am J Transplant. 2019 Oct;19(10):2795-2804
pubmed: 30953600
Pharmacology. 2000 Sep;61(3):199-203
pubmed: 10971206
Front Genet. 2021 Mar 12;12:626845
pubmed: 33777099
Int J Epidemiol. 2020 Feb 1;49(1):23-24k
pubmed: 31378813
Clin Pharmacol Ther. 2020 Jan;107(1):154-170
pubmed: 31544239
Am J Transplant. 2016 Feb;16(2):574-82
pubmed: 26485092
Pharmacotherapy. 2021 Mar;41(3):265-276
pubmed: 33202062
J Clin Oncol. 2005 Dec 20;23(36):9312-8
pubmed: 16361630
Per Med. 2021 May;18(3):311-327
pubmed: 33787318