RENEB/EURADOS field exercise 2019: robust dose estimation under outdoor conditions based on the dicentric chromosome assay.


Journal

International journal of radiation biology
ISSN: 1362-3095
Titre abrégé: Int J Radiat Biol
Pays: England
ID NLM: 8809243

Informations de publication

Date de publication:
2021
Historique:
pubmed: 18 6 2021
medline: 23 9 2021
entrez: 17 6 2021
Statut: ppublish

Résumé

Biological and/or physical assays for retrospective dosimetry are valuable tools to recover the exposure situation and to aid medical decision making. To further validate and improve such biological and physical assays, in 2019, EURADOS Working Group 10 and RENEB performed a field exercise in Lund, Sweden, to simulate various real-life exposure scenarios. For the dicentric chromosome assay (DCA), blood tubes were located at anthropomorphic phantoms positioned in different geometries and were irradiated with a 1.36 TBq The DCA results were homogeneous between participants and matched well with the reference doses (≥95% of estimates within ±0.5 Gy of the reference). For samples close to the source systematic underestimation could be corrected by accounting for exposure time. Heterogeneity within and between tubes was detected for reference doses as well as for DCA doses estimates. The participants were able to successfully estimate the doses and to provide important information on the exposure scenarios under conditions closely resembling a real-life situation.

Identifiants

pubmed: 34138666
doi: 10.1080/09553002.2021.1941380
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1181-1198

Auteurs

David Endesfelder (D)

Bundesamt für Strahlenschutz, BfS, Oberschleissheim, Germany.

Ursula Oestreicher (U)

Bundesamt für Strahlenschutz, BfS, Oberschleissheim, Germany.

Ulrike Kulka (U)

Bundesamt für Strahlenschutz, BfS, Oberschleissheim, Germany.

Elizabeth A Ainsbury (EA)

Public Health England, CRCE, Didcot, UK.

Jayne Moquet (J)

Public Health England, CRCE, Didcot, UK.

Stephen Barnard (S)

Public Health England, CRCE, Didcot, UK.

Eric Gregoire (E)

Institut de Radioprotection et de Sûreté Nucléaire, Fontenay-aux-Roses, France.

Juan S Martinez (JS)

Institut de Radioprotection et de Sûreté Nucléaire, Fontenay-aux-Roses, France.

François Trompier (F)

Institut de Radioprotection et de Sûreté Nucléaire, Fontenay-aux-Roses, France.

Yoann Ristic (Y)

Institut de Radioprotection et de Sûreté Nucléaire, Fontenay-aux-Roses, France.

Clemens Woda (C)

Helmholtz Zentrum München, Institute of Radiation Medicine, Neuherberg, Germany.

Lovisa Waldner (L)

Department of Translational Medicine, Medical Radiation Physics, Lund University, Malmö, Sweden.

Christina Beinke (C)

Bundeswehr Institute of Radiobiology, Munich, Germany.

Anne Vral (A)

Faculty of Medicine and Health Sciences, Universiteit Gent, Gent, Belgium.

Joan-Francesc Barquinero (JF)

Department of Animal Biology, Plant Biology and Ecology, Universitat Autònoma de Barcelona, Bellaterra, Spain.

Alfredo Hernandez (A)

Department of Animal Biology, Plant Biology and Ecology, Universitat Autònoma de Barcelona, Bellaterra, Spain.
Independent Researcher, London, UK.

Sylwester Sommer (S)

Institut Chemii i Techniki Jadrowej, Warszawa, Poland.

Katalin Lumniczky (K)

Department of Radiobiology and Radiohygiene, Unit of Radiation Medicine, National Public Health Centre, Budapest, Hungary.

Rita Hargitai (R)

Department of Radiobiology and Radiohygiene, Unit of Radiation Medicine, National Public Health Centre, Budapest, Hungary.

Alegría Montoro (A)

Laboratorio de Dosimetría Biológica, Servicio de Protección Radiológica Hospital, Universitario Politécnico la Fe, Valencia, Spain.

Mirta Milic (M)

Institute for Medical Research and Occupational Health Mutagenesis Unit, Zagreb, Croatia.

Octávia Monteiro Gil (O)

Centro de Ciências e Tecnologias Nucleares, Instituto Superior Técnico, Universidade de Lisboa, Lisbon, Portugal.

Marco Valente (M)

Department of Radiation Biological, Armed Forces Biomedical Research Institute, Brétigny-sur-Orge, France.

Laure Bobyk (L)

Department of Radiation Biological, Armed Forces Biomedical Research Institute, Brétigny-sur-Orge, France.

Olga Sevriukova (O)

Department of Expertise and Exposure Monitoring, Radiation Protection Centre, Vilnius, Lithuania.

Laure Sabatier (L)

PROCyTOX, Commissariat à l'Energie Atomique et aux Energies Alternatives, Fontenay-aux-Roses, France.
Graduate School Life Science and Health, Université Paris, Saclay, France.

María Jesús Prieto (MJ)

Laboratorio de Dosimetría Biológica, Hospital General Universitario Gregorio Marañón, Madrid, Spain.

Mercedes Moreno Domene (M)

Laboratorio de Dosimetría Biológica, Hospital General Universitario Gregorio Marañón, Madrid, Spain.

Antonella Testa (A)

Agenzia Nazionale per le Nuove Tecnologie, L'energia e lo Sviluppo Economico Sostenibile, Rome, Italy.

Clarice Patrono (C)

Agenzia Nazionale per le Nuove Tecnologie, L'energia e lo Sviluppo Economico Sostenibile, Rome, Italy.

Georgia Terzoudi (G)

Health Physics, Radiobiology and Cytogenetics Laboratory, National Centre for Scientific Research 'Demokritos', Athens, Greece.

Sotiria Triantopoulou (S)

Health Physics, Radiobiology and Cytogenetics Laboratory, National Centre for Scientific Research 'Demokritos', Athens, Greece.

Rositsa Histova (R)

Department of Radiobiology, National Centre of Radiobiology and Radiation Protection, Sofia, Bulgaria.

Andrzej Wojcik (A)

Department of Molecular Biosciences, The Wenner-Gren Institute, Stockholm University, Sweden.
Institute of Biology, Jan Kochanowski University, Kielce, Poland.

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