Genetic Mutations Associated with Hormone-Positive Breast Cancer in a Small Cohort of Ethiopian Women.


Journal

Annals of biomedical engineering
ISSN: 1573-9686
Titre abrégé: Ann Biomed Eng
Pays: United States
ID NLM: 0361512

Informations de publication

Date de publication:
Aug 2021
Historique:
received: 30 10 2020
accepted: 24 05 2021
pubmed: 19 6 2021
medline: 21 1 2022
entrez: 18 6 2021
Statut: ppublish

Résumé

In Ethiopia, a breast cancer diagnosis is associated with a prognosis significantly worse than that of Europe and the US. Further, patients presenting with breast cancer in Ethiopia are far younger, on average, and patients are typically diagnosed at very late stages, relative to breast cancer patients of European descent. Emerging data suggest that a large proportion of Ethiopian patients have hormone-positive (ER

Identifiants

pubmed: 34142276
doi: 10.1007/s10439-021-02800-4
pii: 10.1007/s10439-021-02800-4
pmc: PMC9703640
mid: NIHMS1847068
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1900-1908

Subventions

Organisme : NCI NIH HHS
ID : R21 CA223783
Pays : United States
Organisme : National Science Foundation
ID : 1451512
Organisme : NCI NIH HHS
ID : DP2 CA186573
Pays : United States
Organisme : NCI NIH HHS
ID : DP2CA186573
Pays : United States
Organisme : NCI NIH HHS
ID : R21CA223783
Pays : United States
Organisme : Division of Materials Research
ID : DMR1454806

Informations de copyright

© 2021. Biomedical Engineering Society.

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Auteurs

Alyssa D Schwartz (AD)

Department of Chemical Engineering, University of Massachusetts Amherst, Amherst, MA, USA.

Afua Adusei (A)

Molecular and Cell Biology Graduate Program, University of Massachusetts Amherst, Amherst, MA, USA.

Solomon Tsegaye (S)

Department of Biochemistry, School of Medicine, Addis Ababa University, Addis Ababa, Ethiopia.

Christopher A Moskaluk (CA)

Department of Pathology, University of Virginia Health System, Charlottesville, VA, USA.

Sallie S Schneider (SS)

Molecular and Cell Biology Graduate Program, University of Massachusetts Amherst, Amherst, MA, USA.
Pioneer Valley Life Sciences Institute, Springfield, MA, USA.

Manu O Platt (MO)

Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology and Emory University, 950 Atlantic Drive, Suite 3015, Atlanta, GA, 30332, USA.

Daniel Seifu (D)

Department of Biochemistry, School of Medicine, Addis Ababa University, Addis Ababa, Ethiopia.
Department of Biochemistry, Division of Basic Sciences, University of Global Health Equity, Kigali, Rwanda.

Shelly R Peyton (SR)

Department of Chemical Engineering, University of Massachusetts Amherst, Amherst, MA, USA. speyton@umass.edu.
Molecular and Cell Biology Graduate Program, University of Massachusetts Amherst, Amherst, MA, USA. speyton@umass.edu.
Institute for Applied Life Sciences, University of Massachusetts Amherst, Amherst, MA, USA. speyton@umass.edu.

Courtney C Babbitt (CC)

Molecular and Cell Biology Graduate Program, University of Massachusetts Amherst, Amherst, MA, USA. cbabbitt@bio.umass.edu.
Department of Biology, University of Massachusetts Amherst, Amherst, MA, USA. cbabbitt@bio.umass.edu.
Institute for Applied Life Sciences, University of Massachusetts Amherst, Amherst, MA, USA. cbabbitt@bio.umass.edu.

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Classifications MeSH