A Machine Learning Approach to the Interpretation of Cardiopulmonary Exercise Tests: Development and Validation.


Journal

Pulmonary medicine
ISSN: 2090-1844
Titre abrégé: Pulm Med
Pays: Egypt
ID NLM: 101558762

Informations de publication

Date de publication:
2021
Historique:
received: 10 02 2021
revised: 25 04 2021
accepted: 20 05 2021
entrez: 23 6 2021
pubmed: 24 6 2021
medline: 15 1 2022
Statut: epublish

Résumé

At present, there is no consensus on the best strategy for interpreting the cardiopulmonary exercise test's (CPET) results. This study is aimed at assessing the potential of using computer-aided algorithms to evaluate CPET data for identifying chronic heart failure (CHF) and chronic obstructive pulmonary disease (COPD). Data from 234 CPET files from the Pulmonary Institute, at Sheba Medical Center, and the Givat-Washington College, both in Israel, were selected for this study. The selected CPET files included patients with confirmed primary CHF ( The disease classification results show that the overall predictive power of the proposed interpretive model ranged from 96% to 100%, indicating very high predictive power. Furthermore, the sensitivity, specificity, and overall precision of the proposed interpretive module were 99%, 99%, and 99%, respectively. The proposed new computer-aided CPET interpretive module was found to be highly sensitive and specific in classifying patients with CHF or COPD, or healthy. Comparable modules may well be applied to additional and larger populations (pathologies and exercise limitations), thereby making this tool powerful and clinically applicable.

Identifiants

pubmed: 34158976
doi: 10.1155/2021/5516248
pmc: PMC8188599
doi:

Types de publication

Journal Article Validation Study

Langues

eng

Sous-ensembles de citation

IM

Pagination

5516248

Informations de copyright

Copyright © 2021 Or Inbar et al.

Déclaration de conflit d'intérêts

The authors declare that there are no conflicts of interest regarding the publication of this paper.

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Auteurs

Or Inbar (O)

Department of Biomedical Engineering, Tel-Aviv University, Israel.

Omri Inbar (O)

The Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, Israel.

Ronen Reuveny (R)

Pulmonary Institute, Sheba Medical Center Tel-Hashomer, Israel.

Michael J Segel (MJ)

Pulmonary Institute, Sheba Medical Center Tel-Hashomer, Israel.
Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.

Hayit Greenspan (H)

Department of Biomedical Engineering, Tel-Aviv University, Israel.

Mickey Scheinowitz (M)

Department of Biomedical Engineering, Tel-Aviv University, Israel.

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Classifications MeSH