Risk Factors for Klebsiella Infections among Hospitalized Patients with Preexisting Colonization.


Journal

mSphere
ISSN: 2379-5042
Titre abrégé: mSphere
Pays: United States
ID NLM: 101674533

Informations de publication

Date de publication:
30 06 2021
Historique:
pubmed: 24 6 2021
medline: 15 12 2021
entrez: 23 6 2021
Statut: ppublish

Résumé

Klebsiella commonly colonizes the intestinal tract of hospitalized patients and is a leading cause of health care-associated infections. Colonization is associated with subsequent infection, but the factors determining this progression are unclear. A cohort study was performed, in which intensive care and hematology/oncology patients with Klebsiella colonization based on rectal swab culture were enrolled and monitored for infection for 90 days after a positive swab. Electronic medical records were analyzed for patient factors associated with subsequent infection, and variables of potential significance in a bivariable analysis were used to build a final multivariable model. Concordance between colonizing and infecting isolates was assessed by

Identifiants

pubmed: 34160237
doi: 10.1128/mSphere.00132-21
pmc: PMC8265626
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Pagination

e0013221

Subventions

Organisme : NIAID NIH HHS
ID : R01 AI125307
Pays : United States
Organisme : NIAID NIH HHS
ID : T32 AI007528
Pays : United States

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Auteurs

Krishna Rao (K)

Division of Infectious Diseases, Department of Internal Medicine, University of Michigan Medical Schoolgrid.471406.0, Michigan Medicine, Ann Arbor, Michigan, USA.

Alieysa Patel (A)

Department of Pathology, University of Michigan Medical Schoolgrid.471406.0, Michigan Medicine, Ann Arbor, Michigan, USA.

Yuang Sun (Y)

Department of Pathology, University of Michigan Medical Schoolgrid.471406.0, Michigan Medicine, Ann Arbor, Michigan, USA.

Jay Vornhagen (J)

Department of Pathology, University of Michigan Medical Schoolgrid.471406.0, Michigan Medicine, Ann Arbor, Michigan, USA.

Jonathan Motyka (J)

Division of Infectious Diseases, Department of Internal Medicine, University of Michigan Medical Schoolgrid.471406.0, Michigan Medicine, Ann Arbor, Michigan, USA.

Abigail Collingwood (A)

Department of Pathology, University of Michigan Medical Schoolgrid.471406.0, Michigan Medicine, Ann Arbor, Michigan, USA.

Alexandra Teodorescu (A)

Department of Pathology, University of Michigan Medical Schoolgrid.471406.0, Michigan Medicine, Ann Arbor, Michigan, USA.

Ji Hoon Baang (JH)

Division of Infectious Diseases, Department of Internal Medicine, University of Michigan Medical Schoolgrid.471406.0, Michigan Medicine, Ann Arbor, Michigan, USA.

Lili Zhao (L)

Department of Biostatistics, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA.

Keith S Kaye (KS)

Division of Infectious Diseases, Department of Internal Medicine, University of Michigan Medical Schoolgrid.471406.0, Michigan Medicine, Ann Arbor, Michigan, USA.

Michael A Bachman (MA)

Department of Pathology, University of Michigan Medical Schoolgrid.471406.0, Michigan Medicine, Ann Arbor, Michigan, USA.
Department of Microbiology and Immunology, University of Michigan Medical Schoolgrid.471406.0, Michigan Medicine, Ann Arbor, Michigan, USA.

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Classifications MeSH