Prevalence of sleepiness and associations with quality of life in patients with sleep apnea in an online cohort.


Journal

Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine
ISSN: 1550-9397
Titre abrégé: J Clin Sleep Med
Pays: United States
ID NLM: 101231977

Informations de publication

Date de publication:
01 12 2021
Historique:
pubmed: 26 6 2021
medline: 24 12 2021
entrez: 25 6 2021
Statut: ppublish

Résumé

Excessive daytime sleepiness (EDS) is a treatment target for many patients with obstructive sleep apnea (OSA). We aimed to understand the prevalence, risk factors, and quality of life associated with EDS in a nonclinical, "real world" sample of patients with OSA. Cross-sectional survey of patients with OSA participating in an online peer support community, assessing demographics, comorbidities, treatment, and quality of life. Differences in those with and without EDS (Epworth Sleepiness Scale > and ≤ 10) were assessed. The sample (n = 422) was 54.2% male, 65.9% were ≥ 55 years, and 43.3% reported sleeping ≤ 6 hours/night. EDS was identified among 31.0% of respondents and 51.7% reported sleepiness as a precipitating factor for seeking initial OSA treatment. EDS was more prevalent in individuals reporting asthma, insomnia symptoms, positive airway pressure (PAP) use less than 6 hours/night on ≥ 5 nights/week, or sleep duration < 6 hours/night. After adjusting for demographics and comorbidities, patients with EDS reported poorer mental and physical health and well-being, lower disease-specific functional status, more activity and work impairment, and more driving impairment ( These "real world" data suggest that patients seeking online OSA support experience a high prevalence of EDS, which was associated with poorer quality of life and worse functional status. Associations persisted among respondents with high self-reported PAP-therapy adherence, potentially driving these individuals to seek online support for sleepiness-related symptoms. Wanberg LJ, Rottapel RE, Reid ML, et al. Prevalence of sleepiness and associations with quality of life in patients with sleep apnea in an online cohort.

Identifiants

pubmed: 34170220
pii: jcsm.9436
doi: 10.5664/jcsm.9436
pmc: PMC8726384
doi:

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

2363-2372

Subventions

Organisme : NHLBI NIH HHS
ID : R35 HL135818
Pays : United States

Informations de copyright

© 2021 American Academy of Sleep Medicine.

Références

Eur Respir J. 2009 Sep;34(3):687-93
pubmed: 19357151
Qual Life Res. 2009 May;18(4):415-22
pubmed: 19288223
Am J Respir Crit Care Med. 2004 Sep 15;170(6):665-72
pubmed: 15229096
J Psychiatr Res. 2012 Apr;46(4):422-7
pubmed: 22297274
Sleep. 1992 Aug;15(4):376-81
pubmed: 1519015
Health Technol Assess. 2015 Jun;19(40):1-188
pubmed: 26063688
Chest. 2020 Aug;158(2):776-786
pubmed: 32147246
Otolaryngol Clin North Am. 1999 Apr;32(2):303-31
pubmed: 10385539
Nat Commun. 2019 Aug 13;10(1):3503
pubmed: 31409809
Sleep. 2005 Apr;28(4):472-7
pubmed: 16171292
J Clin Sleep Med. 2009 Dec 15;5(6):573-81
pubmed: 20465027
J Clin Sleep Med. 2019 Feb 15;15(2):301-334
pubmed: 30736888
Thorax. 2014 Mar;69(3):274-9
pubmed: 24287166
J Clin Sleep Med. 2016 Jul 15;12(7):1053-8
pubmed: 27166300
Sleep Med. 2015 Aug;16(8):981-6
pubmed: 26141008
J Sleep Res. 2013 Aug;22(4):389-97
pubmed: 23409736
Eur Heart J Acute Cardiovasc Care. 2019 Dec;8(8):762-770
pubmed: 29206050
Front Neurol. 2015 May 26;6:109
pubmed: 26074865
J Clin Psychol. 2013 Oct;69(10):1066-77
pubmed: 23382086
Sleep. 1994 Oct;17(7):619-23
pubmed: 7846460
Psychosom Med. 2005 Jan-Feb;67(1):98-104
pubmed: 15673630
Sleep Med Clin. 2016 Sep;11(3):353-63
pubmed: 27542881
Sleep. 2001 Feb 1;24(1):96-105
pubmed: 11204058
Proc Am Thorac Soc. 2008 Feb 15;5(2):173-8
pubmed: 18250209
Psychother Psychosom. 2015;84(3):167-76
pubmed: 25831962
J Asthma. 2018 Aug;55(8):844-850
pubmed: 27880055
Sleep. 2009 Jul;32(7):915-9
pubmed: 19639754
Sleep. 2017 Apr 1;40(4):
pubmed: 28419387
J Am Coll Cardiol. 2017 Feb 21;69(7):841-858
pubmed: 28209226
Sleep. 1994 Feb;17(1):84-93
pubmed: 7677805
Eur Respir J. 2009 May;33(5):1062-7
pubmed: 19407048
Multidiscip Respir Med. 2019 Feb 14;14:8
pubmed: 30809382
Sleep. 2014 Jan 01;37(1):51-64
pubmed: 24470695
Sleep Breath. 2015 Dec;19(4):1387-93
pubmed: 25855469
Am J Respir Crit Care Med. 2019 Aug 15;200(4):493-506
pubmed: 30764637
J Clin Epidemiol. 1998 Nov;51(11):1171-8
pubmed: 9817135
Psychiatry Res. 2020 Sep;291:113239
pubmed: 32593854
Sleep Med. 2006 Dec;7(8):607-13
pubmed: 16815750
Sleep Med Rev. 2017 Aug;34:70-81
pubmed: 27568340
J Neurosci. 2007 Sep 12;27(37):10060-71
pubmed: 17855620
J Asthma. 2021 Apr;58(4):481-487
pubmed: 31903810

Auteurs

Lindsey J Wanberg (LJ)

Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, Massachusetts.

Rebecca E Rottapel (RE)

Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, Massachusetts.

Michelle L Reid (ML)

Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, Massachusetts.

Suzanne M Bertisch (SM)

Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, Massachusetts.
Harvard Medical School, Boston, Massachusetts.

Morgan Bron (M)

Jazz Pharmaceuticals, Inc., Palo Alto, California.

Vishesh K Kapur (VK)

Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of Washington, Seattle, Washington.

Shay Bujanover (S)

Jazz Pharmaceuticals, Inc., Palo Alto, California.

Zinta Harrington (Z)

University of New South Wales, Sydney, Australia.

Jessie P Bakker (JP)

Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, Massachusetts.
Harvard Medical School, Boston, Massachusetts.

Sogol Javaheri (S)

Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, Massachusetts.
Harvard Medical School, Boston, Massachusetts.

Mark Hanson (M)

Sleep Apnea Patient-Centered Outcomes Network, Boston, Massachusetts.

Kathleen Figetakis (K)

Sleep Apnea Patient-Centered Outcomes Network, Boston, Massachusetts.

Kathy Page (K)

Sleep Apnea Patient-Centered Outcomes Network, Boston, Massachusetts.

Sherry Hanes (S)

Sleep Apnea Patient-Centered Outcomes Network, Boston, Massachusetts.

Kathleen F Villa (KF)

Jazz Pharmaceuticals, Inc., Palo Alto, California.

Susan Redline (S)

Division of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, Massachusetts.
Harvard Medical School, Boston, Massachusetts.

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Classifications MeSH