Knockout of tac3 genes in zebrafish shows no impairment of reproduction.

Animals Male Neurokinin B / genetics Neuropeptides Reproduction / genetics Zebrafish / metabolism Zebrafish Proteins / genetics
Knockout Reproduction Tac3 Zebrafish

Journal

General and comparative endocrinology
ISSN: 1095-6840
Titre abrégé: Gen Comp Endocrinol
Pays: United States
ID NLM: 0370735

Informations de publication

Date de publication:
15 09 2021
Historique:
received: 23 02 2021
revised: 07 06 2021
accepted: 16 06 2021
pubmed: 29 6 2021
medline: 17 3 2022
entrez: 28 6 2021
Statut: ppublish

Résumé

Neurokinin B (NKB) plays a pivotal role in the regulation of reproduction in vertebrates. However, whether this neuropeptide is dispensable for reproduction in teleosts remains unknown. In order to reveal its authentic functions in fish, in this study, two tachykinin 3 (tac3) genes encoding Nkbs were functional mutated in zebrafish using the Transcription Activator-like Effector Nucleases (TALEN) technology. We established tac3a

Identifiants

DOI: 10.1016/j.ygcen.2021.113839 PMID: 34181932
pubmed: 34181932
pii: S0016-6480(21)00132-5
doi: 10.1016/j.ygcen.2021.113839
pii:
doi:

Substances chimiques

Neuropeptides 0
Zebrafish Proteins 0
Neurokinin B 86933-75-7

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

113839

Informations de copyright

Copyright © 2021 Elsevier Inc. All rights reserved.

Auteurs

Yu Li (Y)

State Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory for Aquatic Economic Animals and Guangdong Provincial Engineering Technology Research Center for Healthy Breeding of Important Economic Fish, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275, China.

TingTing Zhao (T)

State Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory for Aquatic Economic Animals and Guangdong Provincial Engineering Technology Research Center for Healthy Breeding of Important Economic Fish, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275, China.

Yun Liu (Y)

State Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory for Aquatic Economic Animals and Guangdong Provincial Engineering Technology Research Center for Healthy Breeding of Important Economic Fish, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275, China.

Haoran Lin (H)

State Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory for Aquatic Economic Animals and Guangdong Provincial Engineering Technology Research Center for Healthy Breeding of Important Economic Fish, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275, China; Laboratory for Marine Fisheries Science and Food Production Processes, Qingdao National Laboratory for Marine Science and Technology, Qingdao 266373, China; Southern Laboratory of Ocean Science and Engineering (Guangdong, Zhuhai), Zhuhai 519000, China.

Shuisheng Li (S)

State Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory for Aquatic Economic Animals and Guangdong Provincial Engineering Technology Research Center for Healthy Breeding of Important Economic Fish, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275, China. Electronic address: lshuish@mail.sysu.edu.cn.

Yong Zhang (Y)

State Key Laboratory of Biocontrol, Guangdong Provincial Key Laboratory for Aquatic Economic Animals and Guangdong Provincial Engineering Technology Research Center for Healthy Breeding of Important Economic Fish, School of Life Sciences, Sun Yat-Sen University, Guangzhou 510275, China; Laboratory for Marine Fisheries Science and Food Production Processes, Qingdao National Laboratory for Marine Science and Technology, Qingdao 266373, China; Southern Laboratory of Ocean Science and Engineering (Guangdong, Zhuhai), Zhuhai 519000, China. Electronic address: lsszy@mail.sysu.edu.cn.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Knockout of tac3 genes in zebrafish shows no...
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Kinines › Tachykinines › Neurokinine B › Knockout of tac3 genes in zebrafish shows no...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines de tissu nerveux › Neuropeptides › Knockout of tac3 genes in zebrafish shows no...
questionsmedicales.fr › Phénomènes physiologiques des appareils urinaire et reproducteur › Phénomènes physiologiques de la reproduction › Reproduction › Knockout of tac3 genes in zebrafish shows no...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Poissons › Cypriniformes › Cyprinidae › Danio zébré › Knockout of tac3 genes in zebrafish shows no...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines de poisson › Protéines de poisson-zèbre › Knockout of tac3 genes in zebrafish shows no...