Preemptive analgesia for endoscopic sinus surgery: a retrospective study.


Journal

Rhinology
ISSN: 0300-0729
Titre abrégé: Rhinology
Pays: Netherlands
ID NLM: 0347242

Informations de publication

Date de publication:
01 Aug 2021
Historique:
pubmed: 30 6 2021
medline: 7 8 2021
entrez: 29 6 2021
Statut: ppublish

Résumé

Chronic rhinosinusitis (CRS) is a common disease, and endoscopic sinus surgery (ESS) is widely performed. However, there is no consensus regarding postoperative pain control after ESS, and postoperative opioid abuse is a problem in many countries. Acetaminophen is reportedly effective for postoperative pain control. Preemptive analgesia has received more attention lately, wherein pain is prevented before it occurs. In this study, we assessed the use of acetaminophen for preemptive analgesia during the perioperative period in ESS. This is a retrospective study of 175 patients who underwent ESS, septoplasty, and bilateral inferior turbinate mucosal resection at our hospital from April 2016 to February 2018. In total, 82 patients received 1,000 mg of acetaminophen during surgery and 4 hours after the first dose, while 93 patients did not receive it routinely. We compared these two groups. The primary outcome was the need to use additional analgesics prescribed by the ward physician and the secondary outcomes included postoperative pain, postoperative bleeding, reoperation, blood pressure, and body temperature. The use of additional oral and intravenous analgesics was significantly reduced in the patients who received acetaminophen perioperatively. Preemptive analgesia during the perioperative period of ESS could lead to satisfactory postoperative pain control.

Sections du résumé

BACKGROUND BACKGROUND
Chronic rhinosinusitis (CRS) is a common disease, and endoscopic sinus surgery (ESS) is widely performed. However, there is no consensus regarding postoperative pain control after ESS, and postoperative opioid abuse is a problem in many countries. Acetaminophen is reportedly effective for postoperative pain control. Preemptive analgesia has received more attention lately, wherein pain is prevented before it occurs. In this study, we assessed the use of acetaminophen for preemptive analgesia during the perioperative period in ESS.
METHODOLOGY METHODS
This is a retrospective study of 175 patients who underwent ESS, septoplasty, and bilateral inferior turbinate mucosal resection at our hospital from April 2016 to February 2018. In total, 82 patients received 1,000 mg of acetaminophen during surgery and 4 hours after the first dose, while 93 patients did not receive it routinely. We compared these two groups. The primary outcome was the need to use additional analgesics prescribed by the ward physician and the secondary outcomes included postoperative pain, postoperative bleeding, reoperation, blood pressure, and body temperature.
RESULTS RESULTS
The use of additional oral and intravenous analgesics was significantly reduced in the patients who received acetaminophen perioperatively.
CONCLUSION CONCLUSIONS
Preemptive analgesia during the perioperative period of ESS could lead to satisfactory postoperative pain control.

Identifiants

pubmed: 34185822
pii: 2830
doi: 10.4193/Rhin20.624
doi:

Substances chimiques

Analgesics, Opioid 0
Acetaminophen 362O9ITL9D

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

398-401

Auteurs

D Nakashima (D)

Department of Otorhinolaryngology, The Jikei University School of Medicine, Tokyo, Japan.

E Mori (E)

Department of Otorhinolaryngology, The Jikei University School of Medicine, Tokyo, Japan.

T Takeda (T)

Department of Otorhinolaryngology, The Jikei University School of Medicine, Tokyo, Japan.

Y Hosokawa (Y)

Department of Otorhinolaryngology, The Jikei University School of Medicine, Tokyo, Japan.

S Takaishi (S)

Department of Otorhinolaryngology, The Jikei University School of Medicine, Tokyo, Japan.

K Omura (K)

Department of Otorhinolaryngology, The Jikei University School of Medicine, Tokyo, Japan.

H Kojima (H)

Department of Otorhinolaryngology, The Jikei University School of Medicine, Tokyo, Japan.

N Otori (N)

Department of Otorhinolaryngology, The Jikei University School of Medicine, Tokyo, Japan.

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Classifications MeSH