Impact of Admission Hyperglycemia on Heart Failure Events and Mortality in Patients With Takotsubo Syndrome at Long-term Follow-up: Data From HIGH-GLUCOTAKO Investigators.
Journal
Diabetes care
ISSN: 1935-5548
Titre abrégé: Diabetes Care
Pays: United States
ID NLM: 7805975
Informations de publication
Date de publication:
09 2021
09 2021
Historique:
received:
22
02
2021
accepted:
24
05
2021
pubmed:
1
7
2021
medline:
21
10
2021
entrez:
30
6
2021
Statut:
ppublish
Résumé
To investigate admission hyperglycemia effects on the sympathetic system and long-term prognosis in Takotsubo syndrome (TTS). In patients with TTS and hyperglycemia (n = 28) versus normoglycemia (n = 48), serum norepinephrine and At hospitalization, those with hyperglycemia versus normoglycemia had higher levels of inflammatory markers and B-type natriuretic peptide and lower left ventricular ejection fraction. Glucose values correlated with norepinephrine levels ( Patients with TTS and hyperglycemia exhibit sympathetic overactivity with a hyperglycemia-mediated proinflammatory pathway, which could cause worse prognosis during follow-up.
Identifiants
pubmed: 34187841
pii: dc21-0433
doi: 10.2337/dc21-0433
doi:
Substances chimiques
3-Iodobenzylguanidine
35MRW7B4AD
Banques de données
ClinicalTrials.gov
['NCT04684004']
figshare
['10.2337/figshare.14673414']
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
2158-2161Commentaires et corrections
Type : CommentIn
Type : CommentIn
Informations de copyright
© 2021 by the American Diabetes Association.