The recombinant plant Bauhinia bauhinioides elastase inhibitor reduces rat thrombus without alterations in hemostatic parameters.
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
29 06 2021
29 06 2021
Historique:
received:
01
12
2020
accepted:
10
06
2021
entrez:
30
6
2021
pubmed:
1
7
2021
medline:
9
11
2021
Statut:
epublish
Résumé
The anti-inflammatory effects of the plant protease inhibitor BbCI (Bauhinia bauhinioides cruzipain inhibitor), which blocks elastase, cathepsin G, and L, and proteinase 3 has been demonstrated. Here, we investigated the recombinant rBbCI-His
Identifiants
pubmed: 34188079
doi: 10.1038/s41598-021-92745-4
pii: 10.1038/s41598-021-92745-4
pmc: PMC8241853
doi:
Substances chimiques
Plant Proteins
0
Recombinant Proteins
0
Serine Proteinase Inhibitors
0
Pancreatic Elastase
EC 3.4.21.36
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
13475Références
Nat Med. 2010 Aug;16(8):887-96
pubmed: 20676107
J Biol Chem. 1989 Jun 25;264(18):10493-500
pubmed: 2732232
J Thromb Haemost. 2009 Dec;7(12):1951-61
pubmed: 19765210
J Thromb Haemost. 2013 Jun;11 Suppl 1:111-21
pubmed: 23809115
J Exp Med. 2012 Apr 9;209(4):819-35
pubmed: 22451716
Curr Emerg Hosp Med Rep. 2013 Apr 21;1(2):83-97
pubmed: 23687625
Eur J Immunol. 2003 May;33(5):1351-60
pubmed: 12731061
Expert Rev Clin Immunol. 2014 May;10(5):593-619
pubmed: 24678812
Biol Chem. 2005 Jun;386(6):561-8
pubmed: 16006243
Arterioscler Thromb Vasc Biol. 2008 Mar;28(3):387-91
pubmed: 18296594
J Intern Med. 2005 Apr;257(4):319-28
pubmed: 15788001
J Thromb Haemost. 2005 Mar;3(3):514-21
pubmed: 15748242
Thromb Res. 1980 Jun 1;18(5):669-74
pubmed: 7414553
FEBS Lett. 2000 Nov 10;484(3):184-8
pubmed: 11078875
Thromb Haemost. 2008 Jan;99(1):44-51
pubmed: 18217133
J Biol Chem. 1995 Jan 20;270(3):1408-15
pubmed: 7836408
Arterioscler Thromb Vasc Biol. 1995 Feb;15(2):258-68
pubmed: 7749835
Blood. 1995 Oct 1;86(7):2767-73
pubmed: 7545470
Blood Cells Mol Dis. 2015 Feb;54(2):206-9
pubmed: 25465717
J Thromb Haemost. 2016 Mar;14(3):551-8
pubmed: 26712312
Nature. 1999 Apr 22;398(6729):718-23
pubmed: 10227295
J Biol Chem. 1997 Apr 25;272(17):11636-47
pubmed: 9111081
Lancet. 2017 Dec 17;388(10063):3060-3073
pubmed: 27375038
Semin Immunopathol. 2012 Jan;34(1):5-30
pubmed: 21818701
Front Endocrinol (Lausanne). 2014 May 13;5:67
pubmed: 24860547
Nat Rev Immunol. 2006 Jul;6(7):541-50
pubmed: 16799473
J Clin Invest. 2012 Jul;122(7):2331-6
pubmed: 22751108
Trends Immunol. 2018 Aug;39(8):610-623
pubmed: 29776849
Ann Rheum Dis. 2011 Jun;70(6):1083-6
pubmed: 21285115
Front Immunol. 2016 Jun 30;7:261
pubmed: 27446090
J Thromb Haemost. 2016 Jul;14(7):1480-3
pubmed: 27428935
Br J Pharmacol. 2007 Jul;151(6):837-43
pubmed: 17533420
Am J Med. 1962 Nov;33:621-47
pubmed: 13936892
Int Angiol. 2017 Aug;36(4):295-298
pubmed: 28263045
Bioorg Med Chem Lett. 2015 Oct 15;25(20):4370-81
pubmed: 26358162
J Pharmacol Exp Ther. 1979 Aug;210(2):243-6
pubmed: 458631
Eur J Pharmacol. 2010 Mar 25;630(1-3):137-44
pubmed: 20043903
J Thromb Haemost. 2013 Jun;11 Suppl 1:233-41
pubmed: 23809127
Handb Exp Pharmacol. 2012;(207):43-61
pubmed: 22566220
Biochem J. 1996 Nov 1;319 ( Pt 3):873-9
pubmed: 8920993
Br J Pharmacol. 2010 Oct;161(4):899-910
pubmed: 20860667
J Vasc Bras. 2018 Oct-Dec;17(4):310-317
pubmed: 30787949
Biochemistry. 2006 Aug 1;45(30):9104-20
pubmed: 16866356
J Exp Med. 1996 Oct 1;184(4):1213-23
pubmed: 8879192
Arterioscler Thromb Vasc Biol. 2014 Nov;34(11):2363-71
pubmed: 25304324
J Thromb Haemost. 2013 Feb;11(2):223-33
pubmed: 23279708
Arterioscler Thromb Vasc Biol. 1997 Dec;17(12):3399-405
pubmed: 9437185
J Clin Pathol Suppl (R Coll Pathol). 1970;4:86-101
pubmed: 5293392
J Cell Mol Med. 2010 Jan;14(1-2):175-80
pubmed: 19659457
J Clin Pathol. 1974 Jul;27(7):517-28
pubmed: 4138834
Chest. 2001 Jan;119(1 Suppl):64S-94S
pubmed: 11157643
Thromb Haemost. 2008 Dec;100(6):1068-75
pubmed: 19132232
Biol Chem. 2001 May;382(5):847-52
pubmed: 11517940
Proc Natl Acad Sci U S A. 2010 Sep 7;107(36):15880-5
pubmed: 20798043
Annu Rev Physiol. 2011;73:527-45
pubmed: 21034220
Front Immunol. 2019 Jun 14;10:1348
pubmed: 31258531
Thromb Haemost. 2017 Feb 28;117(3):437-444
pubmed: 27975101
Clin Exp Immunol. 2001 Dec;126(3):584-8
pubmed: 11737080
Immunol Rev. 2016 Sep;273(1):232-48
pubmed: 27558338
Blood. 2016 Aug 11;128(6):753-62
pubmed: 27354721
Am J Pathol. 1974 Mar;74(3):507-32
pubmed: 4814899