From Genetics to Histomolecular Characterization: An Insight into Colorectal Carcinogenesis in Lynch Syndrome.

Carcinogenesis / genetics Colorectal Neoplasms, Hereditary Nonpolyposis / etiology DNA Mismatch Repair / genetics Female Genetic Predisposition to Disease Germ-Line Mutation Humans Male Models, Biological Phenotype Risk Factors
CRC Lynch syndrome MMR genes early detection

Journal

International journal of molecular sciences
ISSN: 1422-0067
Titre abrégé: Int J Mol Sci
Pays: Switzerland
ID NLM: 101092791

Informations de publication

Date de publication:
23 Jun 2021
Historique:
received: 28 04 2021
revised: 18 06 2021
accepted: 21 06 2021
entrez: 2 7 2021
pubmed: 3 7 2021
medline: 17 7 2021
Statut: epublish

Résumé

Lynch syndrome is a hereditary cancer-predisposing syndrome caused by germline defects in DNA mismatch repair (MMR) genes such as

Identifiants

DOI: 10.3390/ijms22136767 PMID: 34201893 PMC: PMC8268977
pubmed: 34201893
pii: ijms22136767
doi: 10.3390/ijms22136767
pmc: PMC8268977
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Associazione Italiana per la Ricerca sul Cancro
ID : IG-23794
Organisme : Ministero dell'Istruzione, dell'Università e della Ricerca
ID : PRIN 2017, 2017WNKSLr-LS4
Organisme : Ministero della Salute
ID : ricerca corrente 2018-2020
Organisme : Ministero della Salute
ID : ricerca corrente 2019-2021

Références

Nat Genet. 2001 Oct;29(2):137-8
pubmed: 11586295
Cancers (Basel). 2019 Dec 09;11(12):
pubmed: 31835379
J Clin Oncol. 2012 Dec 10;30(35):4409-15
pubmed: 23091106
Genes Chromosomes Cancer. 2009 Apr;48(4):340-50
pubmed: 19156873
Cancer Prev Res (Phila). 2012 Apr;5(4):574-82
pubmed: 22262812
Hepatogastroenterology. 2003 Nov-Dec;50(54):1756-60
pubmed: 14696398
Clin Colon Rectal Surg. 2012 Jun;25(2):103-10
pubmed: 23730225
N Engl J Med. 1998 May 21;338(21):1481-7
pubmed: 9593786
Gastroenterology. 2020 Apr;158(5):1326-1333
pubmed: 31926173
Gut. 2008 Jan;57(1):65-70
pubmed: 17682000
BMC Urol. 2016 Mar 24;16:15
pubmed: 27013479
Diagnostics (Basel). 2020 Jun 28;10(7):
pubmed: 32605302
Endoscopy. 2009 Apr;41(4):316-22
pubmed: 19340735
Oncol Lett. 2019 Mar;17(3):3048-3054
pubmed: 30867733
Fam Cancer. 2018 Jan;17(1):63-69
pubmed: 28573495
Gastroenterology. 2019 May;156(6):1661-1674.e11
pubmed: 30738046
Int J Cancer. 2021 Apr 1;148(7):1652-1657
pubmed: 33284993
Am J Gastroenterol. 2015 Feb;110(2):288-98
pubmed: 25601014
J Natl Cancer Inst. 2010 Feb 3;102(3):193-201
pubmed: 20028993
Mol Cancer. 2020 Mar 2;19(1):49
pubmed: 32122376
Nature. 2012 Aug 30;488(7413):660-4
pubmed: 22895193
Cancer. 2017 Jun 1;123(11):1912-1924
pubmed: 28323334
Gastrointest Endosc. 2003 Dec;58(6 Suppl):S3-43
pubmed: 14652541
J Clin Oncol. 2018 Oct 10;36(29):2961-2968
pubmed: 30161022
PLoS One. 2015 Mar 27;10(3):e0121980
pubmed: 25816162
Proc Natl Acad Sci U S A. 1999 Jul 20;96(15):8681-6
pubmed: 10411935
Gut. 2002 Mar;50(3):382-6
pubmed: 11839719
Nat Med. 1996 Jun;2(6):630-1
pubmed: 8640546
Nat Genet. 2004 Aug;36(8):790-2
pubmed: 15284845
Gastrointest Endosc. 2007 Oct;66(4):639-49
pubmed: 17643437
Mod Pathol. 2020 Dec;33(12):2591-2601
pubmed: 32620917
Urology. 2015 Dec;86(6):1212-7
pubmed: 26385421
Cancer Prev Res (Phila). 2008 Nov;1(6):470-5
pubmed: 19138994
PLoS One. 2007 May 02;2(5):e399
pubmed: 17476321
J Genet Couns. 2018 Feb;27(1):131-139
pubmed: 28780754
Dig Endosc. 2019 Jul;31(4):363-371
pubmed: 30624835
Gastroenterology. 2005 Sep;129(3):837-45
pubmed: 16143123
Clin Pharmacokinet. 2018 Apr;57(4):427-437
pubmed: 29063517
Int J Mol Sci. 2019 Oct 03;20(19):
pubmed: 31623387
Mod Pathol. 2012 May;25(5):722-30
pubmed: 22322191
Clin Genet. 2009 Feb;75(2):141-9
pubmed: 19215248
J Gastroenterol. 2006 Mar;41(3):185-92
pubmed: 16699851
J Natl Cancer Inst. 2004 Feb 18;96(4):261-8
pubmed: 14970275
Am J Gastroenterol. 2005 Oct;100(10):2167-73
pubmed: 16181364
EBioMedicine. 2019 Jan;39:280-291
pubmed: 30578081
JAMA Oncol. 2017 Dec 1;3(12):1702-1706
pubmed: 28772289
Clin Gastroenterol Hepatol. 2005 Sep;3(9):897-902
pubmed: 16234028
iScience. 2020 Oct 07;23(10):101604
pubmed: 33205017
Gut Liver. 2021 Jan 15;15(1):31-43
pubmed: 32340435
Int J Cancer. 2021 Feb 15;148(4):800-811
pubmed: 32683684
Gastroenterology. 2010 Feb;138(2):487-92
pubmed: 19900449
Gut. 2017 Mar;66(3):464-472
pubmed: 26657901
Epigenomics. 2020 Dec;12(24):2173-2187
pubmed: 33350853
Oncogene. 2003 Sep 29;22(42):6479-83
pubmed: 14528271
Lancet Oncol. 2012 Jun;13(6):598-606
pubmed: 22552011
Mod Pathol. 2017 Aug;30(8):1144-1151
pubmed: 28548127
Curr Drug Targets. 2018;19(1):21-37
pubmed: 28699513
Gastroenterology. 2004 Apr;126(4):1190-3
pubmed: 15057757
Fam Cancer. 2008;7(2):157-62
pubmed: 17929199
Br J Cancer. 2013 Jun 25;108(12):2542-8
pubmed: 23703248
Endoscopy. 2013;45(4):257-64
pubmed: 23440588
J Med Genet. 2015 Aug;52(8):553-6
pubmed: 26101330
Gastroenterology. 2008 Aug;135(2):419-28
pubmed: 18602922
Gastroenterology. 2007 Oct;133(4):1093-8
pubmed: 17919485
Gastrointest Endosc. 1996 Jul;44(1):8-14
pubmed: 8836710
Fam Cancer. 2017 Oct;16(4):491-500
pubmed: 28528517
Cancer Biomark. 2006;2(1-2):69-86
pubmed: 17192061
Endoscopy. 2017 Apr;49(4):342-350
pubmed: 28107763
Clin Epigenetics. 2017 Mar 9;9:25
pubmed: 28293326
Clin Epigenetics. 2015 Jul 22;7:71
pubmed: 26203307
Br J Cancer. 2015 Aug 11;113(4):686-92
pubmed: 26247575
Transl Oncol. 2017 Apr;10(2):190-196
pubmed: 28182994
Hum Mol Genet. 2007 Apr 15;16 Spec No 1:R14-20
pubmed: 17613544
Nature. 2012 Jul 18;487(7407):330-7
pubmed: 22810696
Gut. 2018 Jul;67(7):1306-1316
pubmed: 28754778
Int J Cancer. 2008 Jul 15;123(2):444-449
pubmed: 18398828
Pathologica. 2016 Sep;108(3):104-109
pubmed: 28195261
Gastroenterology. 1999 Jun;116(6):1453-6
pubmed: 10348829
Gastroenterology. 2004 Jan;126(1):42-8
pubmed: 14699485
Am J Gastroenterol. 2015 Feb;110(2):223-62; quiz 263
pubmed: 25645574
JAMA. 2011 Jun 8;305(22):2304-10
pubmed: 21642682
Gastroenterology. 2018 Sep;155(3):844-851
pubmed: 29758216
Am J Gastroenterol. 1994 Nov;89(11):1978-80
pubmed: 7942721
Clin Gastroenterol Hepatol. 2011 Apr;9(4):340-3
pubmed: 21070872
Gastroenterology. 2018 Nov;155(5):1400-1409.e2
pubmed: 30063918
Am J Gastroenterol. 2011 Jun;106(6):1110-8
pubmed: 21326223
Genet Med. 2019 Dec;21(12):2706-2712
pubmed: 31204389
Cancer Res. 2001 Nov 1;61(21):7798-802
pubmed: 11691795
Oncotarget. 2017 Nov 24;9(4):5492-5508
pubmed: 29435196
J Genet Couns. 2014 Feb;23(1):38-47
pubmed: 23674164
Clin Gastroenterol Hepatol. 2020 Nov 3;:
pubmed: 33157315
Hered Cancer Clin Pract. 2020 Mar 14;18:6
pubmed: 32190163
Cell. 2000 Oct 13;103(2):295-309
pubmed: 11057902
Fam Cancer. 2016 Oct;15(4):579-86
pubmed: 26960970
Int J Cancer. 2018 Jul 1;143(1):139-150
pubmed: 29424427
Nat Commun. 2017 May 03;8:14755
pubmed: 28466842

Auteurs

Martina Lepore Signorile (M)

Medical Genetics, National Institute for Gastroenterology, IRCCS "S. de Bellis" Research Hospital, 70013 Castellana Grotte, Italy.

Vittoria Disciglio (V)

Medical Genetics, National Institute for Gastroenterology, IRCCS "S. de Bellis" Research Hospital, 70013 Castellana Grotte, Italy.

Gabriella Di Carlo (G)

Department of Emergency and Organ Transplantation, Section of Pathology, University of Bari Aldo Moro, 70124 Bari, Italy.
ORCID: 0000-0001-6258-4193

Antonio Pisani (A)

Gastroenterology and Digestive Endoscopy Unit, National Institute for Gastroenterology, IRCCS "S. de Bellis" Research Hospital, 70013 Castellana Grotte, Italy.

Cristiano Simone (C)

Medical Genetics, National Institute for Gastroenterology, IRCCS "S. de Bellis" Research Hospital, 70013 Castellana Grotte, Italy.
Medical Genetics, Department of Biomedical Sciences and Human Oncology (DIMO), University of Bari Aldo Moro, 70124 Bari, Italy.

Giuseppe Ingravallo (G)

Department of Emergency and Organ Transplantation, Section of Pathology, University of Bari Aldo Moro, 70124 Bari, Italy.
ORCID: 0000-0002-4792-3545

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female

Evaluation of Low-Value Services Across Major Medicare Advantage Insurers and Traditional Medicare.

Ciara Duggan, Adam L Beckman, Ishani Ganguli et al.
1.00
Humans United States Aged Cross-Sectional Studies Medicare Part C

Effectiveness of Virtual Yoga for Chronic Low Back Pain: A Randomized Clinical Trial.

Hallie Tankha, Devyn Gaskins, Amanda Shallcross et al.
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH

questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Processus néoplasiques › Carcinogenèse › From Genetics to Histomolecular...
questionsmedicales.fr › Maladies métaboliques et nutritionnelles › Maladies métaboliques › Troubles dus à un défaut de réparation de l'ADN › Tumeurs colorectales héréditaires sans polypose › From Genetics to Histomolecular...
questionsmedicales.fr › Phénomènes génétiques › Réparation de l'ADN › Réparation de mésappariement de l'ADN › From Genetics to Histomolecular...
questionsmedicales.fr › Phénomènes génétiques › Génotype › Prédisposition génétique à une maladie › From Genetics to Histomolecular...
questionsmedicales.fr › Phénomènes génétiques › Variation génétique › Mutation › Mutation germinale › From Genetics to Histomolecular...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › From Genetics to Histomolecular...
questionsmedicales.fr › Techniques d'investigation › Modèles théoriques › Modèles biologiques › From Genetics to Histomolecular...
questionsmedicales.fr › Phénomènes génétiques › Phénotype › From Genetics to Histomolecular...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Probabilité › Risque › Facteurs de risque › From Genetics to Histomolecular...