Paper-Based Immunosensors with Bio-Chemiluminescence Detection.
bio-chemiluminescence
biosensor
immunosensor
paper-based
point-of-care
Journal
Sensors (Basel, Switzerland)
ISSN: 1424-8220
Titre abrégé: Sensors (Basel)
Pays: Switzerland
ID NLM: 101204366
Informations de publication
Date de publication:
24 Jun 2021
24 Jun 2021
Historique:
received:
23
05
2021
revised:
15
06
2021
accepted:
21
06
2021
entrez:
2
7
2021
pubmed:
3
7
2021
medline:
7
7
2021
Statut:
epublish
Résumé
Since the introduction of paper-based analytical devices as potential diagnostic platforms a few decades ago, huge efforts have been made in this field to develop systems suitable for meeting the requirements for the point-of-care (POC) approach. Considerable progress has been achieved in the adaptation of existing analysis methods to a paper-based format, especially considering the chemiluminescent (CL)-immunoassays-based techniques. The implementation of biospecific assays with CL detection and paper-based technology represents an ideal solution for the development of portable analytical devices for on-site applications, since the peculiarities of these features create a unique combination for fitting the POC purposes. Despite this, the scientific production is not paralleled by the diffusion of such devices into everyday life. This review aims to highlight the open issues that are responsible for this discrepancy and to find the aspects that require a focused and targeted research to make these methods really applicable in routine analysis.
Identifiants
pubmed: 34202483
pii: s21134309
doi: 10.3390/s21134309
pmc: PMC8271422
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : Ministero dell'Istruzione, dell'Università e della Ricerca
ID : 2017YER72K
Organisme : Ministero dell'Istruzione, dell'Università e della Ricerca
ID : 2017Y2PAB8
Organisme : Partnership for Research and Innovation in the Mediterranean Area
ID : Fedkito
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