A Case of COVID-19 Pregnancy Complicated with Hydrops Fetalis and Intrauterine Death.
COVID-19
SARS-CoV-2
coronavirus
fetal death
hydrops fetalis
placenta
pregnancy
vertical transmission
Journal
Medicina (Kaunas, Lithuania)
ISSN: 1648-9144
Titre abrégé: Medicina (Kaunas)
Pays: Switzerland
ID NLM: 9425208
Informations de publication
Date de publication:
28 Jun 2021
28 Jun 2021
Historique:
received:
05
06
2021
revised:
22
06
2021
accepted:
25
06
2021
entrez:
2
7
2021
pubmed:
3
7
2021
medline:
6
7
2021
Statut:
epublish
Résumé
Coronavirus disease 2019 (COVID-19) has rapidly evolved into a worldwide pandemic causing a serious global public health problem. The risk of vertical transmission of SARS-CoV-2 is still debated, and the consequences of this virus on pregnant women and their fetuses remain unknown. We report a case of pregnancy complicated with hydrops fetalis that developed 7 weeks after recovery from a mild SARS-CoV-2 infection, leading to intrauterine death of the foetus. Evidence of SARS-CoV-2 placentitis was demonstrated by the presence of viral particles in the placenta identified by immunohistochemistry. As we excluded all possible etiological factors for non-immunologic hydrops fetalis, we believe that the fetal consequences of our case are related to vertical transmission of SARS-CoV-2 virus. To the best of our knowledge, this is the second reported case in the literature of COVID-19 infection complicated with hydrops fetalis and intrauterine fetal demise.
Identifiants
pubmed: 34203545
pii: medicina57070667
doi: 10.3390/medicina57070667
pmc: PMC8304331
pii:
doi:
Types de publication
Case Reports
Langues
eng
Sous-ensembles de citation
IM
Références
Medicina (Kaunas). 2020 Jun 22;56(6):
pubmed: 32580461
Am J Obstet Gynecol. 2020 Jul;223(1):111.e1-111.e14
pubmed: 32335053
Pediatr Dev Pathol. 2020 May-Jun;23(3):177-180
pubmed: 32397896
Viruses. 2020 Feb 10;12(2):
pubmed: 32050635
Pathobiology. 2021;88(1):69-77
pubmed: 32950981
Case Rep Womens Health. 2020 Jul 12;27:e00243
pubmed: 32704477
Arch Pathol Lab Med. 2020 Apr 27;:
pubmed: 32338533
Am J Obstet Gynecol MFM. 2020 May;2(2):100107
pubmed: 32292902
Am J Obstet Gynecol MFM. 2021 Apr 29;3(4):100386
pubmed: 33932627
MMWR Morb Mortal Wkly Rep. 2020 Sep 25;69(38):1347-1354
pubmed: 32970655
Placenta. 2020 Sep 15;99:45-49
pubmed: 32755724
Placenta. 2021 Jan 15;104:261-266
pubmed: 33465727
Case Rep Womens Health. 2021 Apr;30:e00289
pubmed: 33527073
Virchows Arch. 2021 May 1;:
pubmed: 33934229
JAMA. 2020 Jun 2;323(21):2198-2200
pubmed: 32352491
Case Rep Obstet Gynecol. 2021 Mar 16;2021:5552877
pubmed: 33763271
MMWR Morb Mortal Wkly Rep. 2020 Sep 23;69(38):1355-1359
pubmed: 32970660
Am J Clin Pathol. 2020 Jun 8;154(1):23-32
pubmed: 32441303
Matern Health Neonatol Perinatol. 2021 Jan 20;7(1):6
pubmed: 33472696
EBioMedicine. 2020 Sep;59:102951
pubmed: 32818801
Obstet Gynecol. 2020 Nov;136(5):1016-1020
pubmed: 32649505
Hum Reprod. 2021 Mar 18;36(4):899-906
pubmed: 33346816