Two
RECK
alternative splicing event
biomarkers
coronary artery disease
splicing variants
Journal
Genes
ISSN: 2073-4425
Titre abrégé: Genes (Basel)
Pays: Switzerland
ID NLM: 101551097
Informations de publication
Date de publication:
19 06 2021
19 06 2021
Historique:
received:
18
05
2021
revised:
10
06
2021
accepted:
15
06
2021
entrez:
2
7
2021
pubmed:
3
7
2021
medline:
22
9
2021
Statut:
epublish
Résumé
Primary prevention is crucial for coronary heart disease (CAD) and the identification of new reliable biomarkers might help risk stratification or predict adverse coronary events. Alternative splicing (AS) is a less investigated genetic factors implicated in CAD etiology. We performed an RNA-seq study on PBMCs from CAD patients and control subjects (CTR) and observed 113 differentially regulated AS events (24 up and 89 downregulated) in 86 genes. The
Identifiants
pubmed: 34205376
pii: genes12060939
doi: 10.3390/genes12060939
pmc: PMC8234100
pii:
doi:
Substances chimiques
Biomarkers
0
GPI-Linked Proteins
0
RECK protein, human
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
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