Successful Treatment of


Journal

Viruses
ISSN: 1999-4915
Titre abrégé: Viruses
Pays: Switzerland
ID NLM: 101509722

Informations de publication

Date de publication:
21 06 2021
Historique:
received: 20 05 2021
revised: 12 06 2021
accepted: 14 06 2021
entrez: 2 7 2021
pubmed: 3 7 2021
medline: 19 1 2022
Statut: epublish

Résumé

Successful joint replacement is a life-enhancing procedure with significant growth in the past decade. Prosthetic joint infection occurs rarely; it is a biofilm-based infection that is poorly responsive to antibiotic alone. Recent interest in bacteriophage therapy has made it possible to treat some biofilm-based infections, as well as those caused by multidrug-resistant pathogens, successfully when conventional antibiotic therapy has failed. Here, we describe the case of a 61-year-old woman who was successfully treated after a second cycle of bacteriophage therapy administered at the time of a two-stage exchange procedure for a persistent methicillin-sensitive

Identifiants

pubmed: 34205687
pii: v13061182
doi: 10.3390/v13061182
pmc: PMC8233819
pii:
doi:

Types de publication

Case Reports

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NIAID NIH HHS
ID : T32 AI007036
Pays : United States

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Auteurs

Claudia Ramirez-Sanchez (C)

Department of Infectious Diseases and Global Public Health, University of California San Diego, La Jolla, CA 92093, USA.

Francis Gonzales (F)

Department of Surgery, University of California San Diego, La Jolla, CA 92093, USA.

Maureen Buckley (M)

Department of Surgery, University of California San Diego, La Jolla, CA 92093, USA.

Biswajit Biswas (B)

Biological Defense Research Directorate, Naval Medical Research Center, Fort Detrick, MD 21702, USA.

Matthew Henry (M)

Biological Defense Research Directorate, Naval Medical Research Center, Fort Detrick, MD 21702, USA.
The Geneva Foundation, Tacoma, WA 98402, USA.

Michael V Deschenes (MV)

Biological Defense Research Directorate, Naval Medical Research Center, Fort Detrick, MD 21702, USA.
Leidos, Reston, VA 20190, USA.

Bri'Anna Horne (B)

Adaptive Phage Therapeutics, Gaithersburg, MD 20878, USA.

Joseph Fackler (J)

Adaptive Phage Therapeutics, Gaithersburg, MD 20878, USA.

Michael J Brownstein (MJ)

Adaptive Phage Therapeutics, Gaithersburg, MD 20878, USA.

Robert T Schooley (RT)

Department of Infectious Diseases and Global Public Health, University of California San Diego, La Jolla, CA 92093, USA.
Center for Innovative Phage Therapy and Applications, University of California San Diego, La Jolla, CA 92093, USA.

Saima Aslam (S)

Department of Infectious Diseases and Global Public Health, University of California San Diego, La Jolla, CA 92093, USA.
Center for Innovative Phage Therapy and Applications, University of California San Diego, La Jolla, CA 92093, USA.

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