Novel Spray Dried Algae-Rosemary Particles Attenuate Pollution-Induced Skin Damage.
cosmeceuticals
herbs
phytochemicals
pollution
Journal
Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009
Informations de publication
Date de publication:
22 Jun 2021
22 Jun 2021
Historique:
received:
17
05
2021
revised:
12
06
2021
accepted:
16
06
2021
entrez:
2
7
2021
pubmed:
3
7
2021
medline:
13
7
2021
Statut:
epublish
Résumé
The present study investigated the effect of spray-dried algae-rosemary particles against pollution-induced damage using ex-vivo human biopsies exposed to diesel engine exhaust (DEE). For this, the complexation of hydroalcoholic rosemary extract with Chlorella (RCH) and Spirulina (RSP) protein powders was conducted. The process efficiency and concentration of rosmarinic acid (RA), carnosic acid (CA), and carnosol (CR) phenolic compounds of both products were compared. The RSP spray-dried production was more efficient, and RSP particles presented higher CR and CA and similar RA concentrations. Therefore, spray-dried RSP particles were prioritized for the preparation of a gel formulation that was investigated for its ability to mitigate pollution-induced skin oxinflammatory responses. Taken altogether, our ex-vivo data clearly demonstrated the ability of RSP gel to prevent an oxinflammatory phenomenon in cutaneous tissue by decreasing the levels of 4-hydroxynonenal protein adducts (4HNE-PA) and active matrix metalloproteinase-9 (MMP-9) as well as by limiting the loss of filaggrin induced by DEE exposure. Our results suggest that the topical application of spirulina-rosemary gel is a good approach to prevent pollution-induced skin aging/damage.
Identifiants
pubmed: 34206295
pii: molecules26133781
doi: 10.3390/molecules26133781
pmc: PMC8270324
pii:
doi:
Substances chimiques
Antioxidants
0
Cinnamates
0
Depsides
0
FLG protein, human
0
Filaggrin Proteins
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : U.S. Department of Agriculture
ID : NIFA Hatch Project 02689, 02669
Références
J Invest Dermatol. 2017 Jun;137(6):1373-1375
pubmed: 28219661
Planta Med. 2010 May;76(7):683-8
pubmed: 19941258
Food Chem. 2013 Jan 15;136(2):1047-54
pubmed: 23122161
J Nutr. 2011 Dec;141(12):2119-25
pubmed: 22031657
Part Fibre Toxicol. 2020 Jul 25;17(1):35
pubmed: 32711561
Ann N Y Acad Sci. 2012 Oct;1271:75-81
pubmed: 23050967
Allergol Int. 2018 Jan;67(1):3-11
pubmed: 29153780
Biofactors. 2019 Jul;45(4):536-547
pubmed: 31087730
Molecules. 2021 Mar 30;26(7):
pubmed: 33808148
Food Funct. 2019 Oct 16;10(10):6286-6299
pubmed: 31524913
Antioxidants (Basel). 2019 Sep 06;8(9):
pubmed: 31500121
Exp Dermatol. 2013 May;22(5):336-41
pubmed: 23614740
Free Radic Biol Med. 2015 Jun;83:262-72
pubmed: 25744415
Sci Total Environ. 2021 Jun 10;772:144905
pubmed: 33770892
Redox Biol. 2020 Jul;34:101481
pubmed: 32336667
Food Chem. 2020 Mar 30;309:125688
pubmed: 31732249
Food Res Int. 2020 Aug;134:109242
pubmed: 32517919
Skin Pharmacol Appl Skin Physiol. 2002 Sep-Oct;15(5):282-90
pubmed: 12239421
Free Radic Biol Med. 2020 May 1;151:111-122
pubmed: 31874249
Molecules. 2016 Apr 08;21(4):465
pubmed: 27070563
J Sep Sci. 2017 Mar;40(5):1057-1062
pubmed: 28008719
Food Chem. 2017 Nov 15;235:76-85
pubmed: 28554650
Front Physiol. 2018 Jul 09;9:858
pubmed: 30038581
Food Chem. 2019 May 15;280:187-194
pubmed: 30642485
Evid Based Complement Alternat Med. 2017;2017:7359806
pubmed: 28286534
Biochem Biophys Res Commun. 2003 Jun 6;305(3):741-6
pubmed: 12763055
Plant Physiol. 2017 Nov;175(3):1381-1394
pubmed: 28916593
Phytother Res. 2020 Aug;34(8):1829-1837
pubmed: 32086980
Crit Rev Food Sci Nutr. 2020 Aug 10;:1-16
pubmed: 32772550
Pharmacol Res. 2013 Oct;76:132-48
pubmed: 23942037
Basic Clin Pharmacol Toxicol. 2015 May;116(5):398-413
pubmed: 25287116
Sci Rep. 2016 Jun 17;6:27995
pubmed: 27313009
Allergy Asthma Immunol Res. 2018 May;10(3):207-215
pubmed: 29676067
Plast Reconstr Surg. 2021 Jan 1;147(1S-2):15S-24S
pubmed: 33347070