GMMA Neisseria meningitidis Salmonella fHbp

Journal

Pathogens (Basel, Switzerland)
ISSN: 2076-0817
Titre abrégé: Pathogens
Pays: Switzerland
ID NLM: 101596317

Informations de publication

Date de publication:
09 Jun 2021
Historique:
received: 30 04 2021
revised: 26 05 2021
accepted: 03 06 2021
entrez: 2 7 2021
pubmed: 3 7 2021
medline: 3 7 2021
Statut: epublish

Résumé

GMMA, outer membrane vesicles resulting from hyperblebbing mutated bacterial strains, are a versatile vaccine platform for displaying both homologous and heterologous antigens. Periplasmic expression is a popular technique for protein expression in the lumen of the blebs. However, the ability of internalized antigens to induce antibody responses has not been extensively investigated. Herein, the

Identifiants

pubmed: 34207575
pii: pathogens10060726
doi: 10.3390/pathogens10060726
pmc: PMC8229706
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Francesca Necchi (F)

GSK Vaccines Institute for Global Health, 53100 Siena, Italy.

Giuseppe Stefanetti (G)

GSK Vaccines Institute for Global Health, 53100 Siena, Italy.
Department of Immunology, Blavatnik Institute, Harvard Medical School, Boston, MA 02115, USA.

Renzo Alfini (R)

GSK Vaccines Institute for Global Health, 53100 Siena, Italy.

Elena Palmieri (E)

GSK Vaccines Institute for Global Health, 53100 Siena, Italy.

Martina Carducci (M)

GSK Vaccines Institute for Global Health, 53100 Siena, Italy.

Roberta Di Benedetto (R)

GSK Vaccines Institute for Global Health, 53100 Siena, Italy.

Fabiola Schiavo (F)

GSK Vaccines Institute for Global Health, 53100 Siena, Italy.
Luigi Sacco Department of Biomedical and Clinical Sciences, University of Milan, 20122 Milano, Italy.

Maria Grazia Aruta (MG)

GSK Vaccines Institute for Global Health, 53100 Siena, Italy.

Fabiola Giusti (F)

GSK, 53100 Siena, Italy.
University of Siena, 53100 Siena, Italy.

Ilaria Ferlenghi (I)

GSK, 53100 Siena, Italy.

Yun Shan Goh (YS)

GSK Vaccines Institute for Global Health, 53100 Siena, Italy.
Agency for Science, Technology and Research (A*STAR) Infectious Diseases Labs, Singapore 138648, Singapore.

Simona Rondini (S)

GSK Vaccines Institute for Global Health, 53100 Siena, Italy.
GSK, 53100 Siena, Italy.

Francesca Micoli (F)

GSK Vaccines Institute for Global Health, 53100 Siena, Italy.

Classifications MeSH