Daptomycin: A Novel Macrocyclic Antibiotic as a Chiral Selector in an Organic Polymer Monolithic Capillary for the Enantioselective Analysis of a Set of Pharmaceuticals.
daptomycin
enantioselective
monoliths
nano-HPLC
Journal
Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009
Informations de publication
Date de publication:
09 Jun 2021
09 Jun 2021
Historique:
received:
18
05
2021
revised:
01
06
2021
accepted:
04
06
2021
entrez:
2
7
2021
pubmed:
3
7
2021
medline:
30
7
2021
Statut:
epublish
Résumé
Daptomycin, a macrocyclic antibiotic, is here used as a new chiral selector in preparation of chiral stationary phase (CSP) in a recently prepared polymer monolithic capillary. The latter is prepared using the copolymerization of the monomers glycidyl methacrylate (GMA) and ethylene glycol dimethacrylate (EGDMA) in the presence of daptomycin in water. Under reversed phase conditions (RP), the prepared capillaries were tested for the enantioselective nanoliquid chromatographic separation of fifty of the racemic drugs of different pharmacological groups, such as adrenergic blockers, H1-blockers, NSAIDs, antifungal drugs, and others. Baseline separation was attained for many drugs under RP-HPLC. Daptomycin expands the horizon of chiral selectors in HPLC.
Identifiants
pubmed: 34207780
pii: molecules26123527
doi: 10.3390/molecules26123527
pmc: PMC8227699
pii:
doi:
Substances chimiques
Anti-Bacterial Agents
0
Epoxy Compounds
0
Macrocyclic Compounds
0
Methacrylates
0
Polymers
0
ethylene dimethacrylate
7BK5G69305
Daptomycin
NWQ5N31VKK
glycidyl methacrylate
R8WN29J8VF
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Références
J Chromatogr A. 2006 Mar 10;1108(2):263-7
pubmed: 16464461
Molecules. 2019 Feb 26;24(5):
pubmed: 30813595
J Chromatogr A. 2014 Sep 5;1358:208-16
pubmed: 25047820
J Sep Sci. 2005 Sep;28(14):1675-84
pubmed: 16224961
J Sep Sci. 2006 Jul;29(10):1332-43
pubmed: 16894777
J Antibiot (Tokyo). 1989 Dec;42(12):1790-7
pubmed: 2621162
Talanta. 2013 Oct 15;115:418-21
pubmed: 24054612
J Chromatogr B Analyt Technol Biomed Life Sci. 2014 Oct 1;968:8-21
pubmed: 24661858
J Chromatogr A. 2007 Aug 24;1162(1):90-6
pubmed: 17482626
Anal Bioanal Chem. 2013 Mar;405(7):2123-31
pubmed: 22995998
J Sep Sci. 2006 Aug;29(13):1988-95
pubmed: 17017011
J Food Drug Anal. 2016 Oct;24(4):848-854
pubmed: 28911624
J Chromatogr A. 2001 Jan 12;906(1-2):73-89
pubmed: 11215904
J Sep Sci. 2007 Aug;30(13):2025-36
pubmed: 17625796
Electrophoresis. 1997 Nov;18(12-13):2331-42
pubmed: 9456048
J Chromatogr A. 2017 Sep 15;1515:91-99
pubmed: 28797665
Microbiology (Reading). 2005 May;151(Pt 5):1507-1523
pubmed: 15870461
J Sep Sci. 2006 Jul;29(10):1447-57
pubmed: 16894790
Anal Chem. 2011 May 1;83(9):3616-22
pubmed: 21456603
J Sep Sci. 2019 Jul;42(14):2303-2340
pubmed: 31050176
Anal Chem. 2004 Dec 1;76(23):7013-22
pubmed: 15571354
Anal Chem. 2000 Sep 15;72(18):4394-401
pubmed: 11008775
J Pharm Biomed Anal. 2017 May 10;138:267-271
pubmed: 28231529
J Chromatogr A. 2013 Aug 2;1301:200-8
pubmed: 23806355
J Chromatogr A. 2000 Feb 11;869(1-2):395-409
pubmed: 10720254
Talanta. 2017 Jul 1;169:239-248
pubmed: 28411817
J Chromatogr A. 2012 Dec 7;1267:144-55
pubmed: 23062876
J Chromatogr A. 2013 Jan 25;1274:97-106
pubmed: 23273635
J Antimicrob Chemother. 2005 Mar;55(3):283-8
pubmed: 15705644
J Pharm Biomed Anal. 2015 Oct 10;114:312-20
pubmed: 26099260
Biomed Chromatogr. 2010 Nov;24(11):1213-9
pubmed: 20954213
Prikl Biokhim Mikrobiol. 2006 Nov-Dec;42(6):615-23
pubmed: 17168289
J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Sep 1;1029-1030:174-183
pubmed: 27433982
Anal Chim Acta. 2006 Jan 18;556(1):104-11
pubmed: 17723335
J Bacteriol. 2012 Sep;194(17):4494-504
pubmed: 22661688
J Chromatogr A. 2000 Nov 3;897(1-2):349-63
pubmed: 11128218
Electrophoresis. 2001 Feb;22(3):535-43
pubmed: 11258766
J Chromatogr A. 1999 Sep 3;855(1):273-90
pubmed: 10514993
Electrophoresis. 2002 Feb;23(3):477-85
pubmed: 11870750
Curr Opin Chem Biol. 2009 Apr;13(2):144-51
pubmed: 19303806