Vaccine hesitancy among hospital staff physicians: A cross-sectional survey in France in 2019.


Journal

Vaccine
ISSN: 1873-2518
Titre abrégé: Vaccine
Pays: Netherlands
ID NLM: 8406899

Informations de publication

Date de publication:
22 07 2021
Historique:
received: 10 09 2020
revised: 24 05 2021
accepted: 19 06 2021
pubmed: 3 7 2021
medline: 7 8 2021
entrez: 2 7 2021
Statut: ppublish

Résumé

Healthcare professionals, because they recommend vaccines to their patients, answer their questions, and vaccinate them, are the cornerstone of vaccination in France. They can nonetheless be affected by vaccine hesitancy (VH). We sought to study the opinions, practices, and perceptions of French hospital staff physicians (HSPs) toward vaccination and the prevalence and correlates of VH among them. We conducted a cross-sectional survey in 14 public hospitals in France from September 2018 to October 2019. HSPs completed a standardized questionnaire -most of the time face-to-face - about their vaccine-related attitudes and practices. Data were weighted for age and sex. An agglomerative hierarchical cluster analysis of the HSPs' perceptions and opinions toward vaccination allowed us to identify vaccine-hesitant HSPs, and multiple Poisson regression with robust standard errors let us study the factors associated with VH. The study included 1,795 HSPs (participation rate: 86%). Almost all (93.7%) were strongly favorable to vaccination, even though 42.2% (95CI = 39.8-44.6) showed moderate VH. VH prevalence was lowest among infectious disease specialists (12.3%; 95CI = 6.7-21.3) and pediatricians (27.7%; 95CI = 21.4-35.2). Hesitant HSPs were less trustful of vaccination information sources and doubted the safety of vaccines more often than HSPs with almost no VH. Compared with non-hesitant HSPs, those with higher VH had less often taken a medical course about vaccination and were less likely to be vaccinated against seasonal influenza, to recommend vaccines to their patients and to try to convince vaccine-hesitant patients to be vaccinated. Strong favorability to vaccination does not prevent VH, which was observed in most specialties. Interventions are required to help hesitant HSPs to adopt more proactive vaccination practices.

Sections du résumé

BACKGROUND
Healthcare professionals, because they recommend vaccines to their patients, answer their questions, and vaccinate them, are the cornerstone of vaccination in France. They can nonetheless be affected by vaccine hesitancy (VH).
AIMS
We sought to study the opinions, practices, and perceptions of French hospital staff physicians (HSPs) toward vaccination and the prevalence and correlates of VH among them.
METHODS
We conducted a cross-sectional survey in 14 public hospitals in France from September 2018 to October 2019. HSPs completed a standardized questionnaire -most of the time face-to-face - about their vaccine-related attitudes and practices. Data were weighted for age and sex. An agglomerative hierarchical cluster analysis of the HSPs' perceptions and opinions toward vaccination allowed us to identify vaccine-hesitant HSPs, and multiple Poisson regression with robust standard errors let us study the factors associated with VH.
RESULTS
The study included 1,795 HSPs (participation rate: 86%). Almost all (93.7%) were strongly favorable to vaccination, even though 42.2% (95CI = 39.8-44.6) showed moderate VH. VH prevalence was lowest among infectious disease specialists (12.3%; 95CI = 6.7-21.3) and pediatricians (27.7%; 95CI = 21.4-35.2). Hesitant HSPs were less trustful of vaccination information sources and doubted the safety of vaccines more often than HSPs with almost no VH. Compared with non-hesitant HSPs, those with higher VH had less often taken a medical course about vaccination and were less likely to be vaccinated against seasonal influenza, to recommend vaccines to their patients and to try to convince vaccine-hesitant patients to be vaccinated.
CONCLUSIONS
Strong favorability to vaccination does not prevent VH, which was observed in most specialties. Interventions are required to help hesitant HSPs to adopt more proactive vaccination practices.

Identifiants

pubmed: 34210575
pii: S0264-410X(21)00803-3
doi: 10.1016/j.vaccine.2021.06.053
pii:
doi:

Substances chimiques

Influenza Vaccines 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

4481-4488

Informations de copyright

Copyright © 2021. Published by Elsevier Ltd.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Auteurs

Pierre Verger (P)

Southeastern Health Regional Observatory (Observatoire régional de la santé Paca), Marseille, France; Inserm, F-CRIN, Innovative Clinical Research Network in VACcinology (I-REIVAC), Paris, France.

Christian Dualé (C)

Centre hospitalo-universitaire, Clermont-Ferrand, Centre d'Investigation Clinique, INSERM, CIC1405, Clermont-Ferrand, France; Inserm, F-CRIN, Innovative Clinical Research Network in VACcinology (I-REIVAC), Paris, France.

Nezha Lenzi (N)

Université de Paris, Faculté de médecine Paris Descartes; Inserm, CIC 1417, Assistance Publique Hôpitaux de Paris, Hôpital Cochin, Paris, France; Inserm, F-CRIN, Innovative Clinical Research Network in VACcinology (I-REIVAC), Paris, France.

Dimitri Scronias (D)

Université de Paris, Faculté de médecine Paris Descartes; Inserm, CIC 1417, Assistance Publique Hôpitaux de Paris, Hôpital Cochin, Paris, France. Electronic address: dimitri.scronias@inserm.fr.

Céline Pulcini (C)

Université de Lorraine, APEMAC, équipe MICS, F-54000 Nancy, France; Université de Lorraine, CHRU-Nancy, Infectious Diseases Department, F-54000 Nancy, France.

Odile Launay (O)

Inserm, F-CRIN, Innovative Clinical Research Network in VACcinology (I-REIVAC), Paris, France; Université de Paris, Faculté de médecine Paris Descartes; Inserm, CIC 1417, Assistance Publique Hôpitaux de Paris, Hôpital Cochin, Paris, France.

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