Thebaine is Selectively Demethylated by Thebaine 6-

Binding Sites Biocatalysis Codeine / metabolism Methylation Molecular Dynamics Simulation Oxidoreductases, O-Demethylating / chemistry Protein Conformation Substrate Specificity Thebaine / chemistry

Journal

Inorganic chemistry
ISSN: 1520-510X
Titre abrégé: Inorg Chem
Pays: United States
ID NLM: 0366543

Informations de publication

Date de publication:
19 Jul 2021
Historique:
pubmed: 3 7 2021
medline: 17 8 2021
entrez: 2 7 2021
Statut: ppublish

Résumé

Two homologous 2-oxoglutarate-dependent (ODD) nonheme enzymes thebaine 6-

Identifiants

DOI: 10.1021/acs.inorgchem.1c00468 PMID: 34213893
pubmed: 34213893
doi: 10.1021/acs.inorgchem.1c00468
doi:

Substances chimiques

Thebaine 2P9MKG8GX7
3-O-demethylases EC 1.-
Oxidoreductases, O-Demethylating EC 1.-
Codeine UX6OWY2V7J

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

10199-10214

Auteurs

Warispreet Singh (W)

Department of Chemistry & Chemical Engineering, Queen's University, Belfast BT9 5AG, United Kingdom.

Chenggong Hui (C)

Department of Chemistry & Chemical Engineering, Queen's University, Belfast BT9 5AG, United Kingdom.

Chun Li (C)

Key Lab of Industrial Biocatalysis Ministry of Education, Institute of Biochemical Engineering, Department of Chemical Engineering, Tsinghua University, Beijing 100084, P. R. China.

Meilan Huang (M)

Department of Chemistry & Chemical Engineering, Queen's University, Belfast BT9 5AG, United Kingdom.
ORCID: 0000-0001-9063-8056

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Classifications MeSH

questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Sites de fixation › Thebaine is Selectively Demethylated by Thebaine 6-
questionsmedicales.fr › Métabolisme › Biocatalyse › Thebaine is Selectively Demethylated by Thebaine 6-
questionsmedicales.fr › Composés polycycliques › Hydrocarbures aromatiques polycycliques › Phénanthrènes › Morphinanes › Dérivés de la morphine › Codéine › Thebaine is Selectively Demethylated by Thebaine 6-
questionsmedicales.fr › Métabolisme › Alkylation › Méthylation › Thebaine is Selectively Demethylated by Thebaine 6-
questionsmedicales.fr › Sciences de l'information › Méthodologies informatiques › Simulation numérique › Simulation de dynamique moléculaire › Thebaine is Selectively Demethylated by Thebaine 6-
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Oxidoreductases › Oxidoreductases, (O-demethylating) › Thebaine is Selectively Demethylated by Thebaine 6-
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Conformation moléculaire › Conformation des protéines › Thebaine is Selectively Demethylated by Thebaine 6-
questionsmedicales.fr › Phénomènes chimiques › Phénomènes biochimiques › Spécificité du substrat › Thebaine is Selectively Demethylated by Thebaine 6-
questionsmedicales.fr › Composés polycycliques › Hydrocarbures aromatiques polycycliques › Phénanthrènes › Morphinanes › Dérivés de la morphine › Thébaïne › Thebaine is Selectively Demethylated by Thebaine 6-