Progressive supranuclear palsy: diagnosis and management.

cognition dementia movement disorders supranuclear palsy

Journal

Practical neurology
ISSN: 1474-7766
Titre abrégé: Pract Neurol
Pays: England
ID NLM: 101130961

Informations de publication

Date de publication:
Oct 2021
Historique:
accepted: 13 04 2021
pubmed: 4 7 2021
medline: 26 11 2021
entrez: 3 7 2021
Statut: ppublish

Résumé

Treating patients with progressive supranuclear palsy (PSP) is both effective and rewarding. This review aims to share our experience in the proactive management of PSP, considering the patient, the family and the medical context in which the illness unfolds. There are many opportunities to assist your patients, ameliorate their symptoms, reduce their risks and harm, and guide them through the complex medical, social and legal minefield that characterises life with chronic neurological illness. We summarise the challenges of early diagnosis, consider PSP mimics and the role of investigations in excluding these, and discuss the available pharmacological and non-pharmacological treatment strategies to tackle the common and challenging symptoms of PSP. The best treatment will be patient centred and as part of a multidisciplinary team.

Identifiants

pubmed: 34215700
pii: practneurol-2020-002794
doi: 10.1136/practneurol-2020-002794
pmc: PMC8461411
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

376-383

Informations de copyright

© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: None declared.

Références

Mov Disord. 2017 Jun;32(6):853-864
pubmed: 28467028
Brain. 2020 May 1;143(5):1555-1571
pubmed: 32438414
Arch Neurol. 1964 Apr;10:333-59
pubmed: 14107684
Mov Disord Clin Pract. 2019 Dec 19;7(1):16-24
pubmed: 31970205
Neurology. 2016 May 3;86(18):1736-43
pubmed: 27037234

Auteurs

James B Rowe (JB)

Department of Clinical Neurosciences, University of Cambridge, Cambridge, Cambridgeshire, UK james.rowe@mrc-cbu.cam.ac.uk.
MRC Cognition and Brain Sciences Unit, Cambridge, Cambridgeshire, UK.

Negin Holland (N)

Department of Clinical Neurosciences, University of Cambridge, Cambridge, Cambridgeshire, UK.
Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire, UK.

Timothy Rittman (T)

Department of Clinical Neurosciences, University of Cambridge, Cambridge, Cambridgeshire, UK.
Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire, UK.

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Classifications MeSH