Male genital lichen planus: A retrospective study of 89 cases.
Genital
Lichen planus
Male
Journal
Annales de dermatologie et de venereologie
ISSN: 0151-9638
Titre abrégé: Ann Dermatol Venereol
Pays: France
ID NLM: 7702013
Informations de publication
Date de publication:
Mar 2022
Mar 2022
Historique:
received:
17
12
2020
revised:
12
03
2021
accepted:
15
04
2021
pubmed:
6
7
2021
medline:
23
2
2022
entrez:
5
7
2021
Statut:
ppublish
Résumé
Unlike other types of lichen planus (LP), there are no series concerning male genital LP. To describe the clinical characteristics, diagnosis, and response to treatment of male genital LP. A retrospective study of male patients with genital LP consulting a dermatologist specialized in anogenital diseases between January 2010 and 2019. Demographic data, history, functional signs, clinical characteristics, pathology, complications, and treatment efficacy were collected. Eighty-nine patients were included at four centers. The median age was 51 years. Most patients were uncircumcised and asymptomatic. In 88.8% of cases, only the genital mucosa was involved. Erythema (71%), papules (21.3%), lacy network (15.7%), atrophic lesions (15.7%), erosions (14.6%), and post-inflammatory hyperpigmentation (2.2%) were less frequently observed. Biopsy results confirmed LP in 61.3% of cases but could not rule out other inflammatory genital dermatoses in other cases. Anatomic complications were observed in 30.3% of patients. Topical corticosteroids (TCS) induced remission in most cases. Tacrolimus efficacy was comparable to that of TCS. Male genital LP is a rare inflammatory disorder chiefly affecting uncircumcised men. It is found predominantly on the mucosal component of the penis and presents as non-erosive inflammatory balanitis in most cases, with frequent partial or complete remission on treatment with TCS.
Sections du résumé
BACKGROUND
BACKGROUND
Unlike other types of lichen planus (LP), there are no series concerning male genital LP.
OBJECTIVE
OBJECTIVE
To describe the clinical characteristics, diagnosis, and response to treatment of male genital LP.
PATIENTS AND METHODS
METHODS
A retrospective study of male patients with genital LP consulting a dermatologist specialized in anogenital diseases between January 2010 and 2019. Demographic data, history, functional signs, clinical characteristics, pathology, complications, and treatment efficacy were collected.
RESULTS
RESULTS
Eighty-nine patients were included at four centers. The median age was 51 years. Most patients were uncircumcised and asymptomatic. In 88.8% of cases, only the genital mucosa was involved. Erythema (71%), papules (21.3%), lacy network (15.7%), atrophic lesions (15.7%), erosions (14.6%), and post-inflammatory hyperpigmentation (2.2%) were less frequently observed. Biopsy results confirmed LP in 61.3% of cases but could not rule out other inflammatory genital dermatoses in other cases. Anatomic complications were observed in 30.3% of patients. Topical corticosteroids (TCS) induced remission in most cases. Tacrolimus efficacy was comparable to that of TCS.
CONCLUSION
CONCLUSIONS
Male genital LP is a rare inflammatory disorder chiefly affecting uncircumcised men. It is found predominantly on the mucosal component of the penis and presents as non-erosive inflammatory balanitis in most cases, with frequent partial or complete remission on treatment with TCS.
Identifiants
pubmed: 34218935
pii: S0151-9638(21)00056-9
doi: 10.1016/j.annder.2021.04.007
pii:
doi:
Substances chimiques
Glucocorticoids
0
Tacrolimus
WM0HAQ4WNM
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
28-31Informations de copyright
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