Transport Efficiency of Biofunctionalized Magnetic Particles Tailored by Surfactant Concentration.
Journal
Langmuir : the ACS journal of surfaces and colloids
ISSN: 1520-5827
Titre abrégé: Langmuir
Pays: United States
ID NLM: 9882736
Informations de publication
Date de publication:
20 07 2021
20 07 2021
Historique:
pubmed:
8
7
2021
medline:
28
7
2021
entrez:
7
7
2021
Statut:
ppublish
Résumé
Controlled transport of surface-functionalized magnetic beads in a liquid medium is a central requirement for the handling of captured biomolecular targets in microfluidic lab-on-chip biosensors. Here, the influence of the physiological liquid medium on the transport characteristics of functionalized magnetic particles and on the functionality of the coupled protein is studied. These aspects are theoretically modeled and experimentally investigated for prototype superparamagnetic beads, surface-functionalized with green fluorescent protein immersed in buffer solution with different concentrations of a surfactant. The model reports on the tunability of the steady-state particle substrate separation distance to prevent their surface sticking
Identifiants
pubmed: 34231364
doi: 10.1021/acs.langmuir.1c00900
doi:
Substances chimiques
Surface-Active Agents
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM