Analysis of polyphenols in Aegle marmelos leaf and ameliorative efficacy against diabetic mice through restoration of antioxidant and anti-inflammatory status.
Aegle marmelos
anti-inflammatory
antioxidant
diabetes
polyphenols
Journal
Journal of food biochemistry
ISSN: 1745-4514
Titre abrégé: J Food Biochem
Pays: United States
ID NLM: 7706045
Informations de publication
Date de publication:
04 2022
04 2022
Historique:
revised:
18
06
2021
received:
01
03
2021
accepted:
20
06
2021
pubmed:
13
7
2021
medline:
26
4
2022
entrez:
12
7
2021
Statut:
ppublish
Résumé
The biomedical survey reports edible plant Aegle marmelos has been utilized for centuries by tribal communities in India as a dietary supplement for the management of diabetes. Herein, we have investigated cytotoxicity, cytoprotective and antidiabetic activity of characterized alkaloid-free hydroalcoholic extract of A. marmelos (AFEAM; 200 and 400 mg/kg). Identification of polyphenols and quantification of major compounds were done using UPLC-MS and HPTLC, respectively. AFEAM showed good cytocompatibility and cytoprotective potential against oxidative stress induced by hyperglycemia in HepG
Substances chimiques
Anti-Inflammatory Agents
0
Antioxidants
0
Plant Extracts
0
Polyphenols
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e13852Informations de copyright
© 2021 Wiley Periodicals LLC.
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