[Macrophagic activation syndrome revealing Hodgkin lymphoma: an individual case].
Syndrome d’activation macrophagique révélant un lymphome hodgkinien : à propos d’un cas.
Hemophagocytic lymphohistiocytosis
Hodgkin lymphoma
Macrophagic activation syndrome (SAM)
Journal
Annales de biologie clinique
ISSN: 1950-6112
Titre abrégé: Ann Biol Clin (Paris)
Pays: France
ID NLM: 2984690R
Informations de publication
Date de publication:
01 Aug 2021
01 Aug 2021
Historique:
pubmed:
15
7
2021
medline:
26
10
2021
entrez:
14
7
2021
Statut:
ppublish
Résumé
Macrophagic activation syndrome (SAM) or Hemophagocytic lymphohistiocytosis is a clinical-biological entity of non-specific proliferation and activation of macrophages of the reticulohistiocytic system, with phagocytosis of the figurative elements of blood. It is a rare pathology combining non-specific clinical and biological signs and images of hemophagocytosis. It can be primary or acquired secondary to an infection, an autoimmune or neoplastic disease. While T or NK lymphomas are the classic causes of reactive SAM and its association with Hodgkin lymphoma is exceptional. This is a diagnostic and therapeutic emergency given the risk of development towards a fatal multivisceral failure due to an absence of appropriate support. This is a report of a case of SAM revealing a case of Hodgkin lymphoma in a 35-year-old patient.
Identifiants
pubmed: 34259157
pii: abc.2021.1655
doi: 10.1684/abc.2021.1655
doi:
Types de publication
Case Reports
Journal Article
Langues
fre
Sous-ensembles de citation
IM