Toxicological assessment method for evaluating the occupational risk of dynamic olfactometry assessors.

Occupational health Occupational risk assessment Odorous emissions Olfactometric analysis Olfactometric examiners

Journal

Regulatory toxicology and pharmacology : RTP
ISSN: 1096-0295
Titre abrégé: Regul Toxicol Pharmacol
Pays: Netherlands
ID NLM: 8214983

Informations de publication

Date de publication:
Oct 2021
Historique:
received: 06 05 2021
revised: 01 07 2021
accepted: 09 07 2021
pubmed: 16 7 2021
medline: 8 1 2022
entrez: 15 7 2021
Statut: ppublish

Résumé

The paper aims to propose a new method to evaluate the occupational exposure risk for examiners involved in dynamic olfactometry. Indeed, examiners are possibly exposed to hazardous pollutants potentially present in odorous samples. A standardized method to evaluate the examiners' occupational safety is not yet available and the existing models present some critical aspect if applied to real odorous samples (no uniform reference concentrations applied and presence of compounds for which no toxicity threshold is available). A deepening of assessment procedure to evaluate the occupation exposure risk for olfactometric assessors is necessary. This paper proposes a standardized approach for risk assessment in dynamic olfactometry. The proposed approach allows the quantification synthetic and conservative risk indices. In this model, the use of the hazard index for the odorous mixture was proposed to assess the non-carcinogenic risk; the calculation of the inhalation risk was applied to estimate the carcinogenic risk. Different databases can be used to retrieve proper occupational exposure limits, according to the proposed hierarchical basis. These implementations allow obtaining the complete characterization of real samples which can be used to calculate the minimum dilution factor for protecting the panellists' health.

Identifiants

pubmed: 34265403
pii: S0273-2300(21)00144-6
doi: 10.1016/j.yrtph.2021.105003
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

105003

Informations de copyright

Copyright © 2021 Elsevier Inc. All rights reserved.

Auteurs

Elisa Polvara (E)

Department of Chemistry, Materials and Chemical Engineering "Giulio Natta", Politecnico di Milano, Milano, Italy.

Andrea Spinazzè (A)

Department of Science and High Technology DiSAT, Università degli Studi dell'Insubria, Como, Italy. Electronic address: andrea.spinazze@uninsubria.it.

Marzio Invernizzi (M)

Department of Chemistry, Materials and Chemical Engineering "Giulio Natta", Politecnico di Milano, Milano, Italy.

Andrea Cattaneo (A)

Department of Science and High Technology DiSAT, Università degli Studi dell'Insubria, Como, Italy.

Selena Sironi (S)

Department of Chemistry, Materials and Chemical Engineering "Giulio Natta", Politecnico di Milano, Milano, Italy.

Domenico Maria Cavallo (DM)

Department of Science and High Technology DiSAT, Università degli Studi dell'Insubria, Como, Italy.

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