Thyroid hormones in persons with schizophrenia: A systematic review and meta-analysis.

Datasets as Topic Humans Psychotic Disorders / blood Schizophrenia / blood Thyroid Hormones / blood Thyrotropin / blood Thyroxine / blood Triiodothyronine / blood
Comorbidity Psychoneuroendocrinology Psychotic disorders Thyroid gland

Journal

Progress in neuro-psychopharmacology & biological psychiatry
ISSN: 1878-4216
Titre abrégé: Prog Neuropsychopharmacol Biol Psychiatry
Pays: England
ID NLM: 8211617

Informations de publication

Date de publication:
20 12 2021
Historique:
received: 06 04 2021
revised: 09 07 2021
accepted: 12 07 2021
pubmed: 19 7 2021
medline: 19 2 2022
entrez: 18 7 2021
Statut: ppublish

Résumé

There is accumulating evidence that individuals with schizophrenia show altered levels of thyroid hormones. However, a qualitative and quantitative synthesis of findings in this field has not been performed so far. Therefore, we aimed to perform a systematic review and meta-analysis of studies investigating the levels of thyroid-stimulating hormone (TSH), free thyroxine (fT4), total thyroxine (tT4), free triiodothyronine (fT3) and total triiodothyronine (tT3) in multiple-episode schizophrenia (MES) and first-episode psychosis (FEP). Electronic databases were searched from their inception until 30th May 2020 by two independent reviewers. Random-effects meta-analyses and meta-regression analyses were performed. Altogether, 19 studies were included. Persons with FEP had significantly lower TSH levels (5 studies, g = -0.26, 95%CI: -0.47 to -0.06, p = 0.013, I

Identifiants

DOI: 10.1016/j.pnpbp.2021.110402 PMID: 34274416
pubmed: 34274416
pii: S0278-5846(21)00161-5
doi: 10.1016/j.pnpbp.2021.110402
pii:
doi:

Substances chimiques

Thyroid Hormones 0
Triiodothyronine 06LU7C9H1V
Thyrotropin 9002-71-5
Thyroxine Q51BO43MG4

Types de publication

Journal Article Meta-Analysis Systematic Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

110402

Informations de copyright

Copyright © 2021 The Authors. Published by Elsevier Inc. All rights reserved.

Auteurs

Błażej Misiak (B)

Department of Psychiatry, Division of Consultation Psychiatry and Neuroscience, Wroclaw Medical University, Pasteura 10 Street, 50-367 Wroclaw, Poland; Department of Psychiatry, Wroclaw Medical University, Pasteura 10 Street, 50-367 Wroclaw, Poland. Electronic address: blazej.misiak@umed.wroc.pl.

Bartłomiej Stańczykiewicz (B)

Department of Nervous System Diseases, Wroclaw Medical University, Bartla 5 Street, 51-618 Wroclaw, Poland.

Michał Wiśniewski (M)

First Department of Psychiatry, Institute of Psychiatry and Neurology, Sobieskiego 9 Street, 02-957 Warsaw, Poland.

Francesco Bartoli (F)

Department of Medicine and Surgery, University of Milano Bicocca, Monza, Italy; Department of Mental Health & Addiction, ASST Nord Milano, Milano, Italy.

Giuseppe Carra (G)

Department of Medicine and Surgery, University of Milano Bicocca, Monza, Italy; Department of Mental Health & Addiction, ASST Nord Milano, Milano, Italy; Division of Psychiatry, University College London, London, UK.

Daniele Cavaleri (D)

Department of Medicine and Surgery, University of Milano Bicocca, Monza, Italy.

Jerzy Samochowiec (J)

Department of Psychiatry, Pomeranian Medical University, Broniewskiego 26 Street, 71-460 Szczecin, Poland.

Konrad Jarosz (K)

Department of Clinical Nursing, Pomeranian Medical University, Żołnierska 48 Street, 71-210 Szczecin, Poland.

Joanna Rosińczuk (J)

Department of Nervous System Diseases, Wroclaw Medical University, Bartla 5 Street, 51-618 Wroclaw, Poland.

Dorota Frydecka (D)

Department of Psychiatry, Wroclaw Medical University, Pasteura 10 Street, 50-367 Wroclaw, Poland.

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Classifications MeSH

questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Collecte de données › Jeux de données comme sujet › Thyroid hormones in persons with...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Thyroid hormones in persons with...
questionsmedicales.fr › Troubles mentaux › Schizophrénie et troubles avec traits psychotiques › Troubles psychotiques › Thyroid hormones in persons with...
questionsmedicales.fr › Troubles mentaux › Schizophrénie et troubles avec traits psychotiques › Schizophrénie › Thyroid hormones in persons with...
questionsmedicales.fr › Hormones thyroïdiennes › Thyroid hormones in persons with...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Hormones peptidiques › Hormones hypophysaires › Hormones antéhypophysaires › Thyréostimuline › Thyroid hormones in persons with...
questionsmedicales.fr › Acides aminés, peptides et protéines › Acides aminés › Acides aminés cycliques › Acides aminés aromatiques › Thyroxine › Thyroid hormones in persons with...
questionsmedicales.fr › Acides aminés, peptides et protéines › Acides aminés › Acides aminés cycliques › Acides aminés aromatiques › Thyroxine › Thyronines › Tri-iodothyronine › Thyroid hormones in persons with...