Progression in Moyamoya Disease: Clinical Features, Neuroimaging Evaluation, and Treatment.

Epidemiology Moyamoya disease genetic characteristics neuroimaging pathogenesis progression treatment

Journal

Current neuropharmacology
ISSN: 1875-6190
Titre abrégé: Curr Neuropharmacol
Pays: United Arab Emirates
ID NLM: 101157239

Informations de publication

Date de publication:
2022
Historique:
received: 28 01 2021
revised: 08 05 2021
accepted: 09 07 2021
pubmed: 20 7 2021
medline: 16 3 2022
entrez: 19 7 2021
Statut: ppublish

Résumé

Moyamoya disease (MMD) is a chronic cerebrovascular disease characterized by progressive stenosis of the arteries of the circle of Willis, with the formation of collateral vascular network at the base of the brain. Its clinical manifestations are complicated. Numerous studies have attempted to clarify the clinical features of MMD, including its epidemiology, genetic characteristics, and pathophysiology. With the development of neuroimaging techniques, various neuroimaging modalities with different advantages have deepened the understanding of MMD in terms of structural, functional, spatial, and temporal dimensions. At present, the main treatment for MMD focuses on neurological protection, cerebral blood flow reconstruction, and neurological rehabilitation, such as pharmacological treatment, surgical revascularization, and cognitive rehabilitation. In this review, we discuss recent progress in understanding the clinical features, in the neuroimaging evaluation and treatment of MMD.

Identifiants

pubmed: 34279201
pii: CN-EPUB-116749
doi: 10.2174/1570159X19666210716114016
pmc: PMC9413783
doi:

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

292-308

Subventions

Organisme : National Natural Science Foundation of China
ID : 81771237, 81801155
Organisme : Shanghai Municipal Science and Technology Commission Major Project
ID : 2018SHZDZX03, 19DZ1930304
Organisme : ZJLab, and Shanghai Municipal Commission of Health and Family Planning
ID : 2017BR022, 2019SY076

Informations de copyright

Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

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Auteurs

Xin Zhang (X)

Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Neurosurgical Institute of Fudan University, Shanghai, China.
Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China.
Shanghai Key Laboratory of Brain Function and Restoration and Neural Regeneration, Shanghai, China.
Department of Neurosurgery, Huashan Hospital North, Fudan University, Shanghai, China.

Weiping Xiao (W)

Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Neurosurgical Institute of Fudan University, Shanghai, China.
Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China.
Shanghai Key Laboratory of Brain Function and Restoration and Neural Regeneration, Shanghai, China.
Department of Neurosurgery, Huashan Hospital North, Fudan University, Shanghai, China.

Qing Zhang (Q)

Department of Nursing, Huashan Hospital North, Fudan University, Shanghai, China.

Ding Xia (D)

Department of Radiology, Huashan Hospital North, Fudan University, Shanghai, China.

Peng Gao (P)

Department of Radiology, Huashan Hospital North, Fudan University, Shanghai, China.

Jiabin Su (J)

Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Neurosurgical Institute of Fudan University, Shanghai, China.
Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China.
Shanghai Key Laboratory of Brain Function and Restoration and Neural Regeneration, Shanghai, China.
Department of Neurosurgery, Huashan Hospital North, Fudan University, Shanghai, China.

Heng Yang (H)

Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Neurosurgical Institute of Fudan University, Shanghai, China.
Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China.
Shanghai Key Laboratory of Brain Function and Restoration and Neural Regeneration, Shanghai, China.
Department of Neurosurgery, Huashan Hospital North, Fudan University, Shanghai, China.

Xinjie Gao (X)

Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Neurosurgical Institute of Fudan University, Shanghai, China.
Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China.
Shanghai Key Laboratory of Brain Function and Restoration and Neural Regeneration, Shanghai, China.
Department of Neurosurgery, Huashan Hospital North, Fudan University, Shanghai, China.

Wei Ni (W)

Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Neurosurgical Institute of Fudan University, Shanghai, China.
Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China.
Shanghai Key Laboratory of Brain Function and Restoration and Neural Regeneration, Shanghai, China.
Department of Neurosurgery, Huashan Hospital North, Fudan University, Shanghai, China.

Yu Lei (Y)

Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Neurosurgical Institute of Fudan University, Shanghai, China.
Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China.
Shanghai Key Laboratory of Brain Function and Restoration and Neural Regeneration, Shanghai, China.
Department of Neurosurgery, Huashan Hospital North, Fudan University, Shanghai, China.

Yuxiang Gu (Y)

Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.
Neurosurgical Institute of Fudan University, Shanghai, China.
Shanghai Clinical Medical Center of Neurosurgery, Shanghai, China.
Shanghai Key Laboratory of Brain Function and Restoration and Neural Regeneration, Shanghai, China.
Department of Neurosurgery, Huashan Hospital North, Fudan University, Shanghai, China.

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