Excess all-cause mortality and COVID-19-related mortality: a temporal analysis in 22 countries, from January until August 2020.


Journal

International journal of epidemiology
ISSN: 1464-3685
Titre abrégé: Int J Epidemiol
Pays: England
ID NLM: 7802871

Informations de publication

Date de publication:
18 02 2022
Historique:
accepted: 25 05 2021
pubmed: 21 7 2021
medline: 24 2 2022
entrez: 20 7 2021
Statut: ppublish

Résumé

This study aimed to investigate overall and sex-specific excess all-cause mortality since the inception of the COVID-19 pandemic until August 2020 among 22 countries. Countries reported weekly or monthly all-cause mortality from January 2015 until the end of June or August 2020. Weekly or monthly COVID-19 deaths were reported for 2020. Excess mortality for 2020 was calculated by comparing weekly or monthly 2020 mortality (observed deaths) against a baseline mortality obtained from 2015-2019 data for the same week or month using two methods: (i) difference in observed mortality rates between 2020 and the 2015-2019 average and (ii) difference between observed and expected 2020 deaths. Brazil, France, Italy, Spain, Sweden, the UK (England, Wales, Northern Ireland and Scotland) and the USA demonstrated excess all-cause mortality, whereas Australia, Denmark and Georgia experienced a decrease in all-cause mortality. Israel, Ukraine and Ireland demonstrated sex-specific changes in all-cause mortality. All-cause mortality up to August 2020 was higher than in previous years in some, but not all, participating countries. Geographical location and seasonality of each country, as well as the prompt application of high-stringency control measures, may explain the observed variability in mortality changes.

Sections du résumé

BACKGROUND
This study aimed to investigate overall and sex-specific excess all-cause mortality since the inception of the COVID-19 pandemic until August 2020 among 22 countries.
METHODS
Countries reported weekly or monthly all-cause mortality from January 2015 until the end of June or August 2020. Weekly or monthly COVID-19 deaths were reported for 2020. Excess mortality for 2020 was calculated by comparing weekly or monthly 2020 mortality (observed deaths) against a baseline mortality obtained from 2015-2019 data for the same week or month using two methods: (i) difference in observed mortality rates between 2020 and the 2015-2019 average and (ii) difference between observed and expected 2020 deaths.
RESULTS
Brazil, France, Italy, Spain, Sweden, the UK (England, Wales, Northern Ireland and Scotland) and the USA demonstrated excess all-cause mortality, whereas Australia, Denmark and Georgia experienced a decrease in all-cause mortality. Israel, Ukraine and Ireland demonstrated sex-specific changes in all-cause mortality.
CONCLUSIONS
All-cause mortality up to August 2020 was higher than in previous years in some, but not all, participating countries. Geographical location and seasonality of each country, as well as the prompt application of high-stringency control measures, may explain the observed variability in mortality changes.

Identifiants

pubmed: 34282450
pii: 6324094
doi: 10.1093/ije/dyab123
pmc: PMC8344815
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

35-53

Subventions

Organisme : University of Nicosia Medical School

Commentaires et corrections

Type : CommentIn

Informations de copyright

© The Author(s) 2021; all rights reserved. Published by Oxford University Press on behalf of the International Epidemiological Association.

Auteurs

Souzana Achilleos (S)

Department of Primary Care and Population Health, University of Nicosia Medical School, Nicosia, Cyprus.

Annalisa Quattrocchi (A)

Department of Primary Care and Population Health, University of Nicosia Medical School, Nicosia, Cyprus.

John Gabel (J)

University of Nicosia Medical School, Nicosia, Cyprus.

Alexandros Heraclides (A)

Department of Primary Care and Population Health, University of Nicosia Medical School, Nicosia, Cyprus.

Ourania Kolokotroni (O)

Department of Primary Care and Population Health, University of Nicosia Medical School, Nicosia, Cyprus.

Constantina Constantinou (C)

Department of Basic and Clinical Sciences, University of Nicosia Medical School, Nicosia, Cyprus.

Maider Pagola Ugarte (M)

University of Nicosia Medical School, Nicosia, Cyprus.

Nicoletta Nicolaou (N)

Department of Basic and Clinical Sciences, University of Nicosia Medical School, Nicosia, Cyprus.

Jose Manuel Rodriguez-Llanes (JM)

European Commission Joint Research Centre, Ispra, Italy.

Catherine Marie Bennett (CM)

School of Health and Social Development, Deakin University, Melbourne, Australia.

Ekaterina Bogatyreva (E)

School of Health and Social Development, Deakin University, Melbourne, Australia.

Eva Schernhammer (E)

Department of Epidemiology, Center for Public Health, Medical University of Vienna, Vienna, Austria.

Claudia Zimmermann (C)

Department of Epidemiology, Center for Public Health, Medical University of Vienna, Vienna, Austria.

Antonio Jose Leal Costa (AJL)

Institute of Studies in Collective Health (IESC), Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.

Jackeline Christiane Pinto Lobato (JCP)

Department of Epidemiology and Biostatistics, Institute of Collective Health (ISC), Fluminense Federal University Niterói, Brazil.

Ngibo Mubeta Fernandes (NM)

National Health Observatory, National Institute of Public Health, Praia, Cape Verde.

Ana Paula Semedo-Aguiar (AP)

Nature, Life and Environment Sciences Department, University Jean Piaget of Cape Verde, Praia, Cape Verde.

Gloria Isabel Jaramillo Ramirez (GI)

Medicine Faculty, Cooperative University of Colombia, Villavicencio, Colombia.

Oscar Dario Martin Garzon (OD)

Medicine Faculty, Cooperative University of Colombia, Villavicencio, Colombia.

Laust Hvas Mortensen (LH)

Department of Public Health, University of Copenhagen, Methods and Analysis, Statistics Denmark, Copenhagen, Denmark.

Julia A Critchley (JA)

Population Health Research Institute, St George's, University of London, London, UK.

Lucy P Goldsmith (LP)

Population Health Research Institute, St George's, University of London, London, UK.

Gleb Denissov (G)

Department of Registries, National Institute for Health Development, Tallinn, Estonia.

Kristi Rüütel (K)

Department of Drug and Infectious Diseases Epidemiology, National Institute for Health Development, Tallinn, Estonia.

Nolwenn Le Meur (N)

University of Rennes, EHESP, REPERES-EA 7449, Rennes, France.

Levan Kandelaki (L)

National Center for Disease Control and Public Health, Tbilisi, Georgia.

Shorena Tsiklauri (S)

National Statistics Office of Georgia, Tbilisi, Georgia.

Joan O'Donnell (J)

HSE-Health Protection Surveillance Centre, Dublin, Ireland.

Ajay Oza (A)

HSE-Health Protection Surveillance Centre, Dublin, Ireland.

Zalman Kaufman (Z)

Israel Center of Disease Control, Ministry of Health, Ramat Gan, Israel.

Inbar Zucker (I)

Israel Center of Disease Control, Ministry of Health, Ramat Gan, Israel.
Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Giuseppe Ambrosio (G)

Department of Medicine, University of Perugia School of Medicine, Perugia, Italy.
CERICLET- Interdepartmental Center for Clinical and Translational Research, University of Perugia School of Medicine, Perugia, Italy.

Fabrizio Stracci (F)

Department of Medicine, University of Perugia School of Medicine, Perugia, Italy.

Terje P Hagen (TP)

Department of Health Management and Health Economics, University of Oslo, Oslo, Norway.

Ivan Erzen (I)

Public Health School, National Institute of Public Health, Ljubljana, Slovenia.

Petra Klepac (P)

Communicable Diseases, National Institute of Public Health, Ljubljana, Slovenia.

Pedro Arcos González (P)

Department of Medicine, University of Oviedo, Oviedo, Spain.

Ángel Fernández Camporro (Á)

Department of Medicine, University of Oviedo, Oviedo, Spain.

Bo Burström (B)

Department of Global Public Health, Karolinska Institutet, Stockholm, Sweden.

Nataliia Pidmurniak (N)

Faculty of Medicine, Bogomolets National Medical University, Kyiv, Ukraine.

Olesia Verstiuk (O)

Faculty of Medicine, Bogomolets National Medical University, Kyiv, Ukraine.

Qian Huang (Q)

SC Center for Rural and Primary Health Care and Department of Geography, University of South Carolina, Columbia, SC, USA.

Neil Kishor Mehta (NK)

Department of Preventive Medicine and Population Health, University of Texas Medical Branch, Galveston, TX, USA.

Antonis Polemitis (A)

University of Nicosia, Nicosia, Cyprus.

Andreas Charalambous (A)

University of Nicosia Medical School, Nicosia, Cyprus.

Christiana A Demetriou (CA)

Department of Primary Care and Population Health, University of Nicosia Medical School, Nicosia, Cyprus.

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