Metabolism and Sex Differentiation in Animals from a Starvation Perspective.
Metabolism
Pantothenate
Sex differentiation
Sex reversal
Starvation
Journal
Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation
ISSN: 1661-5433
Titre abrégé: Sex Dev
Pays: Switzerland
ID NLM: 101316472
Informations de publication
Date de publication:
2021
2021
Historique:
received:
04
11
2020
accepted:
12
02
2021
pubmed:
21
7
2021
medline:
15
3
2022
entrez:
20
7
2021
Statut:
ppublish
Résumé
Animals determine their sex genetically (GSD: genetic sex determination) and/or environmentally (ESD: environmental sex determination). Medaka (Oryzias latipes) employ a XX/XY GSD system, however, they display female-to-male sex reversal in response to various environmental changes such as temperature, hypoxia, and green light. Interestingly, we found that 5 days of starvation during sex differentiation caused female-to-male sex reversal. In this situation, the metabolism of pantothenate and fatty acid synthesis plays an important role in sex reversal. Metabolism is associated with other biological factors such as germ cells, HPG axis, lipids, and epigenetics, and supplys substances and acts as signal transducers. In this review, we discuss the importance of metabolism during sex differentiation and how metabolism contributes to sex differentiation.
Identifiants
pubmed: 34284403
pii: 000515281
doi: 10.1159/000515281
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
168-178Informations de copyright
© 2021 The Author(s) Published by S. Karger AG, Basel.