Interventional cardiac MRI using an add-on parallel transmit MR system: In vivo experience in sheep.

MR-guided RF induced heating auxiliary pTx system guidewire visualization guidewires interventional MRI parallel transmission real-time feedback

Journal

Magnetic resonance in medicine
ISSN: 1522-2594
Titre abrégé: Magn Reson Med
Pays: United States
ID NLM: 8505245

Informations de publication

Date de publication:
12 2021
Historique:
revised: 15 06 2021
received: 09 04 2021
accepted: 28 06 2021
pubmed: 22 7 2021
medline: 1 2 2022
entrez: 21 7 2021
Statut: ppublish

Résumé

We present in vivo testing of a parallel transmit system intended for interventional MR-guided cardiac procedures. The parallel transmit system was connected in-line with a conventional 1.5 Tesla MRI system to transmit and receive on an 8-coil array. The system used a current sensor for real-time feedback to achieve real-time current control by determining coupling and null modes. Experiments were conducted on 4 Charmoise sheep weighing 33.9-45.0 kg with nitinol guidewires placed under X-ray fluoroscopy in the atrium or ventricle of the heart via the femoral vein. Heating tests were done in vivo and post-mortem with a high RF power imaging sequence using the coupling mode. Anatomical imaging was done using a combination of null modes optimized to produce a useable B Anatomical imaging produced cine images of the heart comparable in quality to imaging with the quad mode (all channels with the same amplitude and phase). Maximum observed temperature increases occurred when insulation was stripped from the wire tip. These were 4.1℃ and 0.4℃ for the coupling mode and null modes, respectively for the in vivo case; increasing to 6.0℃ and 1.3℃, respectively for the ex vivo case, because cooling from blood flow is removed. Heating < 0.1℃ was observed when insulation was not stripped from guidewire tips. In all tests, the parallel transmit system managed to reduce the temperature at the guidewire tip. We have demonstrated the first in vivo usage of an auxiliary parallel transmit system employing active feedback-based current control for interventional MRI with a conventional MRI scanner.

Identifiants

pubmed: 34286866
doi: 10.1002/mrm.28931
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

3360-3372

Subventions

Organisme : British Heart Foundation
ID : FS/20/26/34952
Pays : United Kingdom
Organisme : Medical Research Council
ID : MR/N027949/1
Pays : United Kingdom
Organisme : Medical Research Council (MRC)
ID : MR/N027949
Organisme : Wellcome Trust
ID : WT 203148/Z/16/Z
Pays : United Kingdom

Informations de copyright

© 2021 The Authors. Magnetic Resonance in Medicine published by Wiley Periodicals LLC on behalf of International Society for Magnetic Resonance in Medicine.

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Auteurs

Felipe Godinez (F)

School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom.
Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom.

Raphael Tomi-Tricot (R)

MR Research Collaborations, Siemens Healthcare Limited, Frimley, United Kingdom.

Marylène Delcey (M)

Centre de Recherche Cardio, Thoracique de Bordeaux/IHU Liryc, INSERM U1045-University of Bordeaux, Pessac, France.
Siemens Healthcare, Saint-Denis, France.

Steven E Williams (SE)

School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom.

Ronald Mooiweer (R)

School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom.

Bruno Quesson (B)

Centre de Recherche Cardio, Thoracique de Bordeaux/IHU Liryc, INSERM U1045-University of Bordeaux, Pessac, France.

Reza Razavi (R)

School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom.

Joseph V Hajnal (JV)

School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom.
Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom.

Shaihan J Malik (SJ)

School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom.
Centre for the Developing Brain, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom.

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