Signal-averaged resting sympathetic transduction of blood pressure: is it time to account for prevailing muscle sympathetic burst frequency?
Action Potentials
Adolescent
Adult
Blood Pressure
Blood Pressure Determination
Cardiovascular System
/ innervation
Electrocardiography
Electromyography
Female
Healthy Volunteers
Heart Rate
Humans
Male
Middle Aged
Muscle, Skeletal
/ innervation
Proof of Concept Study
Retrospective Studies
Signal Processing, Computer-Assisted
Sympathetic Nervous System
/ physiology
Time Factors
Young Adult
muscle sympathetic nerve activity
sex differences
sympathetic transduction
Journal
American journal of physiology. Regulatory, integrative and comparative physiology
ISSN: 1522-1490
Titre abrégé: Am J Physiol Regul Integr Comp Physiol
Pays: United States
ID NLM: 100901230
Informations de publication
Date de publication:
01 09 2021
01 09 2021
Historique:
pubmed:
22
7
2021
medline:
21
10
2021
entrez:
21
7
2021
Statut:
ppublish
Résumé
Calculating the blood pressure (BP) response to a burst of muscle sympathetic nerve activity (MSNA), termed sympathetic transduction, may be influenced by an individual's resting burst frequency. We examined the relationships between sympathetic transduction and MSNA in 107 healthy males and females and developed a normalized sympathetic transduction metric to incorporate resting MSNA. Burst-triggered signal averaging was used to calculate the peak diastolic BP response following each MSNA burst (sympathetic transduction of BP) and following incorporation of MSNA burst cluster patterns and amplitudes (sympathetic transduction slope). MSNA burst frequency was negatively correlated with sympathetic transduction of BP (
Identifiants
pubmed: 34287075
doi: 10.1152/ajpregu.00131.2021
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
R484-R494Subventions
Organisme : CIHR
Pays : Canada
Commentaires et corrections
Type : CommentIn
Type : CommentIn
Type : CommentIn