First or Second Biologic in Inflammatory Bowel Disease: Combination Therapy or Monotherapy?


Journal

Journal of clinical gastroenterology
ISSN: 1539-2031
Titre abrégé: J Clin Gastroenterol
Pays: United States
ID NLM: 7910017

Informations de publication

Date de publication:
01 10 2021
Historique:
pubmed: 24 7 2021
medline: 27 10 2021
entrez: 23 7 2021
Statut: ppublish

Résumé

The therapeutic armamentarium for patients with inflammatory bowel disease has been expanding. Current guidelines make recommendations about whether patients who are biologic naive should be receiving biologic monotherapy or combination therapy, depending on the class of biologics. However, due to the limited available data, guidance to inform clinical practice for patients receiving their second or more biologic are lacking. We hereby review the available data about the use of biologic monotherapy or combination therapy with concomitant immunomodulator therapies in patients receiving their first as well as those receiving their second biologic.

Identifiants

pubmed: 34294654
doi: 10.1097/MCG.0000000000001591
pii: 00004836-202110000-00004
doi:

Substances chimiques

Biological Products 0
Immunologic Factors 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

740-746

Informations de copyright

Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.

Références

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Auteurs

Roni Aoun (R)

Division of Gastroenterology and Hepatology, American University of Beirut Medical Center, Beirut, Lebanon.

Suha Jabak (S)

Division of Gastroenterology and Hepatology, American University of Beirut Medical Center, Beirut, Lebanon.

Fadi H Mourad (FH)

Division of Gastroenterology and Hepatology, American University of Beirut Medical Center, Beirut, Lebanon.

Fadi F Francis (FF)

Division of Gastroenterology and Hepatology, American University of Beirut Medical Center, Beirut, Lebanon.

Miguel Regueiro (M)

Division of Gastroenterology, Hepatology, and Nutrition, Cleveland Clinic, Cleveland, OH.

Jana G Hashash (JG)

Division of Gastroenterology and Hepatology, American University of Beirut Medical Center, Beirut, Lebanon.

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