Intra-fractional per-beam adaptive workflow to mitigate the need for a rotating gantry during MRI-guided proton therapy.

MRI-guided proton therapy RayStation adaptive planning intra-fractional per-beam adaptation patient rotation pediatric abdominal tumors

Journal

Physics in medicine and biology
ISSN: 1361-6560
Titre abrégé: Phys Med Biol
Pays: England
ID NLM: 0401220

Informations de publication

Date de publication:
06 09 2021
Historique:
received: 16 04 2021
accepted: 23 07 2021
pubmed: 24 7 2021
medline: 7 1 2022
entrez: 23 7 2021
Statut: epublish

Résumé

The integration of real-time magnetic resonance imaging (MRI) guidance and proton therapy would potentially improve the proton dose steering capability by reducing daily uncertainties due to anatomical variations. The use of a fixed beamline coupled with an axial patient couch rotation would greatly simplify the proton delivery with MRI guidance. Nonetheless, it is mandatory to assure that the plan quality is not deteriorated by the anatomical deformations due to patient rotation. In this work, an in-house tool allowing for intra-fractional per-beam adaptation of intensity-modulated proton plans (BeamAdapt) was implemented through features available in RayStation. A set of three MRIs was acquired for two healthy volunteers (

Identifiants

pubmed: 34298523
doi: 10.1088/1361-6560/ac176f
doi:

Substances chimiques

Protons 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Informations de copyright

Creative Commons Attribution license.

Auteurs

F Guerreiro (F)

Department of Radiotherapy, University Medical Center Utrecht, Utrecht, The Netherlands.

S Svensson (S)

RaySearch Laboratories AB (PUBL), Stockholm, Sweden.

E Seravalli (E)

Department of Radiotherapy, University Medical Center Utrecht, Utrecht, The Netherlands.

E Traneus (E)

RaySearch Laboratories AB (PUBL), Stockholm, Sweden.

B W Raaymakers (BW)

Department of Radiotherapy, University Medical Center Utrecht, Utrecht, The Netherlands.

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