Variations of enzymatic activity and gene expression in zebrafish (Danio rerio) embryos co-exposed to zearalenone and fumonisin B1.

Animals Fumonisins / toxicity Gene Expression Humans Zearalenone / toxicity Zebrafish / genetics
Combined toxicity Embryonic zebrafish Fumonisin B1 Toxic mechanism Zearalenone

Journal

Ecotoxicology and environmental safety
ISSN: 1090-2414
Titre abrégé: Ecotoxicol Environ Saf
Pays: Netherlands
ID NLM: 7805381

Informations de publication

Date de publication:
01 Oct 2021
Historique:
received: 17 04 2021
revised: 13 07 2021
accepted: 15 07 2021
pubmed: 25 7 2021
medline: 20 8 2021
entrez: 24 7 2021
Statut: ppublish

Résumé

The natural co-occurrence of multiple mycotoxins has been reported in cereals and cereal products worldwide. Even though the dietary exposure to mycotoxins constitutes a serious human health, most reports are limited to the toxic effect of individual mycotoxins. The purpose of the present study was to assess the combined toxic effects of zearalenone (ZEN) and fumonisin B1 (FB1) and the potential interaction of their mixture on zebrafish (Danio rerio) embryos. Our results showed that ZEN possessed the higher toxicity to embryonic zebrafish (7-day LC

Identifiants

DOI: 10.1016/j.ecoenv.2021.112533 PMID: 34303040
pubmed: 34303040
pii: S0147-6513(21)00645-X
doi: 10.1016/j.ecoenv.2021.112533
pii:
doi:

Substances chimiques

Fumonisins 0
fumonisin B1 3ZZM97XZ32
Zearalenone 5W827M159J

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

112533

Informations de copyright

Copyright © 2021 The Authors. Published by Elsevier Inc. All rights reserved.

Auteurs

Guiling Yang (G)

State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Institute of Quality and Standard for Agro-products, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, Zhejiang, China.

Yanhua Wang (Y)

State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Institute of Quality and Standard for Agro-products, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, Zhejiang, China.

Tiancai Wang (T)

Key Laboratory of Agro-Product Quality and Safety of Ministry of Agriculture, Institute of Quality Standards and Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing 100081, China.

Dou Wang (D)

State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Institute of Quality and Standard for Agro-products, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, Zhejiang, China.

Hongbiao Weng (H)

State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Institute of Quality and Standard for Agro-products, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, Zhejiang, China.

Qiang Wang (Q)

State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Institute of Quality and Standard for Agro-products, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, Zhejiang, China.

Chen Chen (C)

Key Laboratory of Agro-Product Quality and Safety of Ministry of Agriculture, Institute of Quality Standards and Testing Technology for Agro-Products, Chinese Academy of Agricultural Sciences, Beijing 100081, China; School of Public Health, Shandong University, Jinan 250012, Shandong, China. Electronic address: chenchen02@caas.cn.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Variations of enzymatic activity and gene...
questionsmedicales.fr › Facteurs biologiques › Toxines biologiques › Mycotoxines › Fumonisines › Variations of enzymatic activity and gene...
questionsmedicales.fr › Phénomènes génétiques › Expression des gènes › Variations of enzymatic activity and gene...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Variations of enzymatic activity and gene...
questionsmedicales.fr › Facteurs biologiques › Toxines biologiques › Mycotoxines › Zéaralénone › Variations of enzymatic activity and gene...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Poissons › Cypriniformes › Cyprinidae › Danio zébré › Variations of enzymatic activity and gene...