A comprehensive insight on the biological potential of embelin and its derivatives.


Journal

Natural product research
ISSN: 1478-6427
Titre abrégé: Nat Prod Res
Pays: England
ID NLM: 101167924

Informations de publication

Date de publication:
Jun 2022
Historique:
pubmed: 27 7 2021
medline: 24 6 2022
entrez: 26 7 2021
Statut: ppublish

Résumé

Naturally occurring bioactive molecules are known for their diverse biological applications such as antimicrobial, anticancer, anti-inflammatory, and analgesic activities. Also, some of the natural products act as medicinal drugs. Further, bioactive cell-permeable molecule embelin has been reported for its diverse biological activities such as antimalarial, anticancer, and anti-inflammatory in the literature. With the continuation of our research work on biologically active molecules, based on structural activity relationship and docking studies of embelin and its derivatives, we have reported target-specific anticancer and antimalarial activities of embelin and its analogs. Also, it has been reported in many recent research articles that embelin and its derivatives are known to possess medicinal properties. This review mainly highlights recent reports on broad-spectrum biological activities of the embelin and its analogs to date.

Identifiants

pubmed: 34304655
doi: 10.1080/14786419.2021.1955361
doi:

Substances chimiques

Anti-Infective Agents 0
Anti-Inflammatory Agents 0
Antimalarials 0
Benzoquinones 0
embelin SHC6U8F5ER

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

3054-3068

Auteurs

N Jeelan Basha (NJ)

Department of Chemistry, Indian Academy Degree College-Autonomous, Bangalore, India.

S M Basavarajaiah (SM)

P.G. Department of Chemistry, Vijaya College, Bangalore, India.

Swathi Baskaran (S)

Department of Chemistry, Indian Academy Degree College-Autonomous, Bangalore, India.

Prasanna Kumar (P)

Department of Chemistry, Indian Academy Degree College-Autonomous, Bangalore, India.

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Classifications MeSH