[Muscle relaxant and reversal practices and impact of reversal modalities on operating room and postoperative room duration - results of a Delphi study].

Pratiques de curarisation/décurarisation et impact des modalités de décurarisation sur les durées en salle opératoire et SSPI – résultats d’une enquête Delphi.
Agents de réversion Chirurgie laproscopique Laparoscopic surgery Neostigmine Neuromuscular block Pharmacoeconomics Reversal agents Sugammadex bloc neuromusculaire

Journal

Annales pharmaceutiques francaises
ISSN: 0003-4509
Titre abrégé: Ann Pharm Fr
Pays: France
ID NLM: 2985176R

Informations de publication

Date de publication:
Mar 2022
Historique:
received: 12 11 2020
revised: 24 06 2021
accepted: 19 07 2021
pubmed: 28 7 2021
medline: 24 2 2022
entrez: 27 7 2021
Statut: ppublish

Résumé

The objectives of this Delphi study are to describe muscle relaxant and reversal practices in France and to seek a consensus on the impact of the reversal method on the time spent in the OR and PACU. A two-round Delphi survey was conducted on a panel of French anesthetists involved in colectomies, hysterectomies or bariatric surgery. The questionnaire was designed in collaboration with a scientific committee and was intended to assess neuromuscular blockade reversal techniques and their impact on time spent in the OR and PACU. The first round gathered data on practices and the second round sought a consensus for the time aspect. Overall, all participants (99%) monitored neuromuscular blockade, with a majority (82%) doing so continuously. Of the participants, 22% routinely used a reversal drug. The time saved in the OR or PACU with sugammadex varied between 1 and 43 minutes depending on the surgery and the neuromuscular blockade reversal method it was compared to. Although SFAR recommendations (French Society of Anesthesia & Intensive Care Medicine) were generally well followed, the use of neuromuscular blockade reversal drugs was observed to be not fully integrated into regular practice, despite the fact that more than half of patients were reported to have residual neuromuscular blockade post-surgery and that sugammadex is known to reduce time spent in the OR and PACU compared to other neuromuscular blockade reversal methods.

Identifiants

pubmed: 34314682
pii: S0003-4509(21)00097-3
doi: 10.1016/j.pharma.2021.07.003
pii:
doi:

Substances chimiques

Neuromuscular Nondepolarizing Agents 0
Pharmaceutical Preparations 0
gamma-Cyclodextrins 0
Neostigmine 3982TWQ96G

Types de publication

Journal Article

Langues

fre

Sous-ensembles de citation

IM

Pagination

227-237

Informations de copyright

Copyright © 2021. Published by Elsevier Masson SAS.

Auteurs

J Raft (J)

Institut de cancérologie de Lorraine, service d'anesthésie, 6, avenue de Bourgogne, 54519 Vandœuvre-lès-Nancy, France.

C Anastasy (C)

Ancien directeur d'hôpital, Fontainebleau France.

E Lambaudie (E)

Institut Paoli Calmettes, département de chirurgie oncologique, 232, boulevard de Sainte-Marguerite, 13009 Marseille, France.

E Saillio (E)

MSD France, Courbevoie, France.

C Mackosso (C)

MSD France, Courbevoie, France. Electronic address: carole.mackosso@msd.com.

N Petrica (N)

MSD France, Courbevoie, France.

C Le Dissez (C)

Department of anesthesia, Hospital Paris Saint-Joseph, 185, rue Raymond-Losserand, 75014 Paris, France.

P Alfonsi (P)

IQVIA France, Courbevoie, France.

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Classifications MeSH