Non-ephedrine constituents from the herbaceous stems of Ephedra sinica.
Antimicrobial activity
Ephedra sinica
Ephedrae Herba
Ephedroside
Flavonoids
Journal
Fitoterapia
ISSN: 1873-6971
Titre abrégé: Fitoterapia
Pays: Netherlands
ID NLM: 16930290R
Informations de publication
Date de publication:
Sep 2021
Sep 2021
Historique:
received:
29
04
2021
revised:
14
07
2021
accepted:
17
07
2021
pubmed:
28
7
2021
medline:
18
9
2021
entrez:
27
7
2021
Statut:
ppublish
Résumé
Three new flavonoids, ephedroside A (1), ephedroside B (2), ephedroside C (3), together with fifty-four known compounds 4-57 were isolated from the EtOH extract of the herbaceous stems of Ephedra sinica. The structures of these compounds were elucidated by spectroscopic techniques, as well as by comparison with literature data. Thirty-eight of these compounds were isolated from the genus Ephedra for the first time. The antimicrobial activities of eight compounds were tested by measuring the minimum inhibitory concentrations (MIC) against bacteria (both Gram positive and Gram negative) and fungi, and were found to be in the range of 0.105-0.926 mM. Among them, compound 2 showed the best antimicrobial activity against Pseudomonas aeruginosa with MIC value of 0.105 mM.
Identifiants
pubmed: 34314801
pii: S0367-326X(21)00173-8
doi: 10.1016/j.fitote.2021.104998
pii:
doi:
Substances chimiques
Anti-Bacterial Agents
0
Flavonoids
0
Phytochemicals
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
104998Informations de copyright
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