Pulmonary hypertension in the child with bronchopulmonary dysplasia.
chronic lung disease
premature
pulmonary vascular disease
sildenafil
vasodilator
Journal
Pediatric pulmonology
ISSN: 1099-0496
Titre abrégé: Pediatr Pulmonol
Pays: United States
ID NLM: 8510590
Informations de publication
Date de publication:
11 2021
11 2021
Historique:
revised:
19
07
2021
received:
20
01
2021
accepted:
20
07
2021
pubmed:
30
7
2021
medline:
24
12
2021
entrez:
29
7
2021
Statut:
ppublish
Résumé
Bronchopulmonary dysplasia (BPD) is the most common chronic lung disease of prematurity resulting from complex interactions of perinatal factors that often lead to prolonged respiratory support and increased pulmonary morbidity. There is also growing appreciation for the dysmorphic pulmonary bed characterized by vascular growth arrest and remodeling, resulting in pulmonary vascular disease and its most severe form, pulmonary hypertension (PH) in children with BPD. In this review, we comprehensively discuss the pathophysiology of PH in children with BPD, evaluate the current recommendations for screening and diagnosis of PH, discern associated comorbid conditions, and outline the current treatment options.
Identifiants
pubmed: 34324276
doi: 10.1002/ppul.25602
pmc: PMC8530892
mid: NIHMS1728824
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
3546-3556Subventions
Organisme : NHLBI NIH HHS
ID : T32 HL105334
Pays : United States
Informations de copyright
© 2021 Wiley Periodicals LLC.
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